Gene interactions and pathways from curated databases and text-mining
CASP8: top 25 interacting genes (chr2:202125258-202152432)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only CASP8-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
Gene:               Hide non-CASP8 interactions     Show top Genes on graph    

Less-frequently mentioned interactions with CASP8, not among the Top 25
Other genes interacting with CASP8. Mouse-over to show number of abstracts or databases. Sorted alphabetically (sort by article count).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

ABCC6 ABCD1 ABL1 ACAD8 ACHE ACIN1 ACSM3
ACTA2 ACTG2 ACTL6A ADCYAP1 ADH5 ADIPOQ ADM
AFP AGTR1 AHSA1 AIM2 AIP AKT3 ALB
ALK ALPI ANG ANGPT1 ANGPT2 ANP32A ANXA1
ANXA5 ANXA6 APAF1 APC APEH APEX1 APIP
APOB APOBEC3D APOE APP AR ARC ARHGDIA
ARID1A ARSA ARSK ASIP ATAD3A ATF2 ATF5
ATG3 ATG4D ATG5 ATM ATN1 ATP5O BACE1
BAD BAG3 BCAP31 BCL2L12 BCL3 BCL5 BCL6
BCL9 BCR BDNF BECN1 BFAR BID BIRC2
BIRC3 BIRC5 BIRC6 BIRC7 BIRC8 BLM BMP1
BMP10 BMP15 BMP2 BMP3 BMP4 BMP5 BMP6
BMP7 BNIP3 BNIP3L BOC BRCA1 C22orf29 CA2
CA8 CALB1 CALM3 CALML3 CALR CAPN1 CAPN10
CAPN11 CAPN12 CAPN13 CAPN14 CAPN15 CAPN2 CAPN3
CAPN5 CAPN6 CAPN7 CAPN8 CAPN9 CAPNS1 CARD10
CARD11 CARD14 CARD16 CARD17 CARD18 CARD6 CARD8
CARD9 CASP1 CASP10 CASP12 CASP14 CASP16 CASP2
CASP3 CASP4 CASP5 CASP6 CASP7 CASP8AP2 CASP9
CAST CAT CCDC88A CCK CCL19 CCL2 CCNC
CCND1 CCNH CCR1 CCR10 CCR2 CCR3 CCR4
CCR5 CCR6 CCR7 CCR8 CCR9 CD14 CD2
CD247 CD3D CD3E CD3G CD4 CD40 CD47
CD79A CD79B CD8A CD8B CDA CDC42 CDC6
CDC73 CDCA5 CDH1 CDK1 CDK10 CDK11A CDK11B
CDK12 CDK13 CDK14 CDK15 CDK16 CDK17 CDK18
CDK19 CDK2 CDK20 CDK3 CDK4 CDK5 CDK6
CDK7 CDK8 CDK9 CDKN1A CENPK CEP104 CEP112
CEP120 CEP128 CEP135 CEP152 CEP164 CEP170 CEP19
CEP192 CEP250 CEP290 CEP350 CEP41 CEP44 CEP55
CEP57 CEP63 CEP68 CEP70 CEP72 CEP76 CEP78
CEP85 CEP89 CEP95 CEP97 CFL1 CFLAR CFTR
CHD3 CHUK CIB1 CISH CLIP3 CLTC COL11A1
COL11A2 COL1A1 COL1A2 COL2A1 COL3A1 COL4A1 COL4A3
COL4A4 COL4A5 COL4A6 COL5A1 COL5A2 COL6A1 COL6A2
COL6A3 COL7A1 COP COPS6 CPA1 CPOX CRADD
CREB1 CREB3 CREB5 CRK CRYAB CSE CSF1
CSF2 CSF3 CTNNB1 CTNNBL1 CTNND1 CTR9 CTRL
CTSB CTSD CTSL CUL1 CUL3 CXCL13 CXCL17
CXCL9 CYCS CYR61 DAP3 DAPK2 DAXX DDIT3
DDX28 DEDD2 DERL1 DES DFFA DFFB DHCR24
DIABLO DIDO1 DISC1 DISC2 DLG1 DNAJC5 DNAJC7
DNASE1 DNASE2 DNTT DST DYRK1A E2F1 E2F2
E2F3 EDA2R EDNRA EEF1A2 EGF EGFR EHMT1
EIF2AK2 EIF2S1 EIF3S10 EIF4A1 EIF4G1 EIF4G2 EIF4G3
ELAVL1 EML2 EMP1 EMP2 EMP3 ENDOG EP300
EPHB2 EPO EPX ERVK-6 ETS1 ETS2 EZR
FADD FAF1 FAM168B FASLG FGF2 FHIT FIS1
FOS FOXO1 FOXO3 FOXP3 FUT1 GAL GATA1
GDNF GHSR GJA1 GLI1 GNA11 GNRH1 GP2
GP5 GP6 GP9 GPI GPX1 GPX3 GRAP2
GRB10 GRB14 GRB2 GRB7 GRIA1 GRK1 GRK4
GRK5 GRK6 GRK7 GRP GSK3B GSN GSTT1
GUCY2D GYS1 GYS2 GZMB H2AFX HCLS1 HDAC1
HDAC2 HDAC4 HDAC6 HGF HIF1A HIP1 HIPK2
HIST1H4A HIST2H2BE HLA-DRB1 HMGB1 HMGCR HMOX1 HNRNPH2
HPR HRD HRK HSF1 HSP90AA1 HSPA5 HSPB1
HSPD1 HTRA1 HTRA2 HTRA3 HTRA4 HTT HUNK
IAPP IARS ICAM1 ID3 IDO1 IFI27 IFI44
IFIH1 IFNA2 IFNB1 IFNG IFT57 IGF1 IGF1R
IGF2 IGFBP3 IKBKB IKBKG IL10 IL11 IL13
IL15 IL16 IL18 IL19 IL1A IL1B IL1R1
IL1R2 IL1RN IL2 IL20 IL21 IL22 IL24
IL25 IL26 IL27 IL3 IL31 IL32 IL33
IL34 IL37 IL4 IL5 IL6 IL7 IL8
IL9 ING1 INS IQGAP1 IRF1 IRF2 IRF3
IRF4 IRF5 IRF6 IRF7 IRF8 IRF9 IRS1
IRS4 ITCH ITGA2 ITGAV ITGB1 ITGB3 ITIH4
JAK1 JAK2 JAK3 JUN KARS KDR KHDRBS1
KLF4 KLK3 KLKB1 KMT2A KRR1 KRT18 LAT
LEO1 LEP LGALS1 LMNB1 LMNB2 LPA LRP1
LRRC59 LY96 LYN LYPLA1 MAGT1 MALT1 MAP1LC3A
MAP1LC3B MAP2 MAP2K1 MAP2K2 MAP2K3 MAP2K4 MAP2K5
MAP2K6 MAP2K7 MAP3K1 MAP3K14 MAP3K7 MAP4K4 MAPK1
MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK15 MAPK3
MAPK4 MAPK6 MAPK7 MAPK8 MAPK9 MAPT MCL1
MDM2 ME2 MED1 MED12 MED13 MED14 MED15
MED17 MED21 MED23 MED24 MED25 MED26 MED4
MED6 MED7 MED8 MEFV MEPE MET MICE
MIF MLYCD MME MMP1 MMP10 MMP11 MMP12
MMP13 MMP14 MMP15 MMP16 MMP17 MMP19 MMP2
MMP20 MMP21 MMP24 MMP25 MMP26 MMP27 MMP28
MMP3 MMP7 MMP8 MMP9 MPST MPZ MSC
MSN MST1 MST1R MT3 MT4 MTA1 MTA2
MTA3 MTOR MUC1 MUC12 MUC13 MUC15 MUC16
MUC17 MUC19 MUC2 MUC20 MUC21 MUC22 MUC4
MUC6 MUC7 MUC8 MYC MYLIP MYO9A NA
NAB1 NAB2 NACA NAIP NANOG NANOS2 NCL
NEFH NFKBIA NGF NLRC4 NLRC5 NLRP1 NLRP3
NLRP5 NLRP7 NOD1 NOD2 NOL3 NOS1 NOS2
NOS3 NOX1 NOX3 NOX4 NOX5 NPM1 NPPA
NPS NPY6R NR0B1 NR1H4 NTF3 NTF4 NTN1
NUAK1 NUCB1 NUCB2 NUP153 NUP210 NUP214 NUP43
NUP62 ODC1 OTUD7B P2RX7 PAEP PAF1 PAK1
PAK2 PAN2 PAN3 PANX1 PARG PARK2 PARK7
PC PCBD1 PCNA PCYT1A PDCD1 PDCD10 PDCD11
PDCD2 PDCD4 PDCD5 PDCD6 PDCD7 PDGFB PDIA6
PDLIM7 PEA15 PGF PGP PI3 PIAS1 PICALM
PIDD PIDD1 PIK3CA PIK3R1 PIN1 PLA2G4B PLCG1
PLD1 PLD2 PLD3 PLD4 PLD5 PLD6 PLEC
PLIN4 PLK1 PLOD2 PMEL PML PNPLA2 POLDIP2
PPARA PPARG PPP1R3A PPP2CA PPP2R1A PPP2R2B PPT1
PRDX2 PRG2 PRG3 PRG4 PRKAA1 PRKAA2 PRKAB1
PRKAB2 PRKACB PRKACG PRKAG1 PRKAG2 PRKAR1A PRKAR1B
PRKAR2A PRKAR2B PRKCA PRKCD PRKCG PRKCI PRKDC
PRNP PSEN1 PSENEN PSMB9 PSMD10 PTBP1 PTCH1
PTEN PTGS2 PTHLH PTK2 PTPN11 PTPN13 PTPN6
PTX3 PTX4 PXN PYCARD QRICH1 QRICH2 RAB10
RAB5A RAC1 RAC2 RAC3 RAD1 RAD17 RAD18
RAD21 RAD50 RAD51 RAD52 RAF1 RALBP1 RALGDS
RANBP2 RARA RASA1 RB1 RBBP4 RBBP7 RBL2
RENBP RHO RIPK1 RIPK2 RIPK3 RIPK4 RNF135
RNF19A RNF34 ROCK1 ROCK2 RPS27 RPS27L RRAS
RUNX3 S100A12 SAA1 SATB1 SDS SEC14L2 SEPT4
SERP2 SERPINA1 SERPINB9 SERPINF1 SETBP1 SETD2 SHC1
SIVA1 SKP1 SLC17A5 SLC9A1 SLCO6A1 SLPI SMAD3
SMAD4 SMAD7 SMARCA2 SMARCA4 SMARCB1 SMARCC1 SMARCC2
SMARCD1 SMARCD2 SMARCE1 SMPD1 SMPD2 SNAP25 SOAT1
SOD1 SOD2 SOD3 SORBS1 SP1 SPARC SPP1
SQSTM1 SRC SREBF1 SREBF2 STAT1 STAT3 STC1
STK24 STS STSP1 STX1A STX2 SUB1 SYF2
SYK SYT1 TAC1 TAC3 TAC4 TARDBP TAT
TCF12 TCF15 TCF19 TCF20 TCF21 TCF23 TCF24
TCF25 TCF3 TCF4 TCF7 TCHP TET1 TET2
TET3 TFAP2A TFCP2 TGFB1 TGFB3 TGM2 THBS1
TICAM2 TIMP3 TLR1 TLR10 TLR2 TLR3 TLR4
TLR5 TLR6 TLR7 TLR8 TLR9 TMED7 TNFAIP3
TNFRSF10A TNFRSF10B TNFRSF1A TNFRSF1B TNFRSF25 TNFRSF8 TNFSF12
TNFSF14 TOP1 TOPORS TRA TRAF1 TRAF2 TRAF3
TRAF4 TRAF5 TRAF6 TRAF7 TRIM25 TRIM28 TSC22D3
TUBA1A TUBA1C TUBB TXN TYR UBB UBC
UBE2D1 UBE2L3 UBR5 UCN UCP2 UPK3B USP2
USP54 VCP VDAC1 VDAC2 VDAC3 VEGFA VIM
VIMP VIP WAS WDR61 WNK1 WNT1 WNT3A
XAF1 XIAP XRCC6 YES1 ZGLP1
Data information
Please see the Gene Interactions Track Manual.