Gene interactions and pathways from curated databases and text-mining
EGFR: top 25 interacting genes (chr7:55086709-55279321)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only EGFR-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
Gene:               Hide non-EGFR interactions     Show top Genes on graph    

Less-frequently mentioned interactions with EGFR, not among the Top 25
Other genes interacting with EGFR. Mouse-over to show number of abstracts or databases. Sorted alphabetically (sort by article count).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

AAK1 ABCG5 ABCG8 ABL1 ABL2 ABLIM1 ABLIM3
ACACA ACOT9 ACSL3 ACTA1 ACTA2 ACTBL2 ACTC1
ACTG1 ACTG2 ACTN1 ACTN4 ACTR2 ACTR3 ADAM10
ADAM11 ADAM12 ADAM15 ADAM17 ADAM18 ADAM19 ADAM2
ADAM20 ADAM21 ADAM22 ADAM23 ADAM28 ADAM29 ADAM30
ADAM32 ADAM33 ADAM5 ADAM6 ADAM7 ADAM8 ADAM9
ADCYAP1R1 ADRA2A ADRB2 ADRB3 ADRBK1 ADRM1 AGO2
AGTR1 AGTR2 AHCYL1 AHNAK AHR AHSA1 AIFM1
AIP AKAP12 ALDH3A2 ALDOA AMH AMPH ANG
ANGPT1 ANGPT2 ANGPT4 ANKRD13A ANKRD13B ANKRD13D ANKS1A
ANKS1B ANO5 ANXA1 ANXA6 AP1B1 AP1G1 AP1G2
AP1M1 AP1M2 AP1S1 AP2A1 AP2A2 AP2B1 AP2M1
AP2S1 APBA3 APBB1 APBB2 APBB3 APPL1 AQP3
AR AREG AREGB ARF4 ARF6 ARFGEF1 ARHGEF5
ARHGEF7 ARL1 ARMC8 ARPC1A ARPC2 ARPC3 ARPC4
ARPC5 ARRB1 ATAD3A ATIC ATP1A1 ATP1B1 ATP2A2
ATP2A3 ATP2B4 ATP5A1 ATP5B ATP5C1 ATP6V1H ATR
ATXN10 ATXN2 B2M BAD BAG1 BAG2 BAIAP2
BAX BCAR1 BCAR3 BCL10 BCL2 BCL3 BCL5
BCL6 BCL9 BCLAF1 BCR BCRP1 BCRP2 BCRP3
BCRP4 BCRP5 BCRP6 BCRP7 BCRP8 BCRP9 BIRC2
BLK BMX BSG BTC BUB3 BZW2 C11orf84
CA2 CALM1 CALM2 CALM3 CALU CAMK2A CAMK2D
CAMK2G CAMLG CANX CAPN1 CAPN10 CAPN11 CAPN12
CAPN13 CAPN14 CAPN15 CAPN2 CAPN3 CAPN5 CAPN6
CAPN7 CAPN8 CAPN9 CAPZB CASP1 CASP10 CASP12
CASP14 CASP16 CASP2 CASP3 CASP4 CASP5 CASP6
CASP7 CASP8 CASP9 CAT CAV1 CAV2 CAV3
CBL CBLB CBLC CBR1 CCAR2 CCDC50 CCL2
CCM2L CCND1 CCT3 CD200R1 CD2AP CD40 CD44
CD59 CD82 CD9 CDC25A CDC37 CDC42 CDCP1
CDH1 CDH10 CDH11 CDH12 CDH13 CDH15 CDH16
CDH17 CDH18 CDH19 CDH2 CDH20 CDH22 CDH23
CDH24 CDH26 CDH3 CDH4 CDH5 CDH6 CDH7
CDH8 CDH9 CDK5 CDKN1A CDX2 CEACAM1 CEBPB
CEND1 CFL1 CFL2 CGA CGB8 CHKB CHMP2B
CHMP3 CHMP5 CISH CKAP4 CLNK CLTA CLTCL1
CMTM8 CNTN2 COA1 COA3 COA4 COA5 COA6
COG1 COG4 COG5 COG6 COG7 COL17A1 COL9A3
CORO1B CORO1C CPD CPOX CR1L CR2 CREB1
CREB3 CREB5 CRK CRKL CSE1L CSF1 CSF2
CSK CSN2 CSN3 CSRP1 CSTA CTGF CTNNA1
CTNNA2 CTNNB1 CTNND1 CTTN CXCL1 CXCL10 CXCL11
CXCL12 CXCL13 CXCL14 CXCL16 CXCL17 CXCL2 CXCL3
CXCL5 CXCL6 CXCL8 CXCL9 CXCR2 CXCR4 CYTH2
DAPP1 DARS DBN1 DBR1 DCBLD2 DCN DCTN2
DDX20 DDX39B DDX3X DDX5 DDX6 DDX60 DEGS1
DFNA5 DHCR7 DHX9 DICER1 DISC1 DISC2 DLD
DLST DNAJA1 DNAJA2 DNAJA3 DNAJB11 DNAJB12 DNAJB2
DNAJB6 DNAJB8 DNAJC10 DNAJC13 DNAJC4 DOCK4 DOK2
DOK4 DOK5 DOK6 DOPEY2 DPP10 DPP3 DPP4
DPP6 DPP7 DPP8 DPP9 DST DUOX1 DUT
DVL1 DYNC1H1 DYNLL1 EDN1 EDNRA EEA1 EEF1A1
EEF1G EEF2 EFNA1 EFNA2 EFNA3 EFNA4 EFNA5
EFNB1 EFNB2 EGR1 EHMT1 EIF2B2 EIF2B3 EIF2B5
EIF4A1 EIF4A3 ENGASE EPAS1 EPB41 EPHB4 EPN1
EPN2 EPN3 EPPK1 EPRS EPS15L1 ERBB2 ERBB2IP
ERBB3 ERBB4 EREG ERVK-6 ESR1 ESR2 EXOC3
EXOC4 EXOC5 EXOC6 EXOC6B EXOC7 EXOC8 F2R
F2RL1 FABP5 FABP7 FADD FAH FAS FASLG
FBXO25 FBXO6 FCHO2 FCRL5 FDFT1 FDPS FER
FES FGB FGF2 FGFR2 FGFR3 FHL2 FKBP4
FKBP8 FLII FLNB FLT4 FOS FOSL1 FPR1
FRS2 FSCN1 FUT1 FYN GAB1 GAB2 GABARAPL2
GABRA5 GABRG1 GABRQ GAPDH GAST GBF1 GCN1L1
GDNF GEMIN4 GEMIN6 GFAP GGCT GMFB GNAI1
GNAI2 GNAI3 GNB1 GNB2 GNB3 GNB4 GNRH1
GNRH2 GOT1 GPER1 GPM6B GPR1 GPR101 GPR107
GPR108 GPR110 GPR111 GPR112 GPR113 GPR114 GPR115
GPR116 GPR119 GPR12 GPR123 GPR124 GPR125 GPR126
GPR128 GPR132 GPR133 GPR135 GPR137 GPR139 GPR141
GPR142 GPR143 GPR144 GPR146 GPR148 GPR149 GPR15
GPR150 GPR151 GPR152 GPR153 GPR155 GPR156 GPR157
GPR158 GPR160 GPR161 GPR162 GPR17 GPR171 GPR173
GPR174 GPR176 GPR179 GPR18 GPR180 GPR182 GPR183
GPR19 GPR20 GPR21 GPR22 GPR25 GPR26 GPR27
GPR3 GPR31 GPR32 GPR33 GPR34 GPR35 GPR36
GPR37 GPR37L1 GPR39 GPR4 GPR42 GPR45 GPR50
GPR52 GPR55 GPR56 GPR6 GPR61 GPR62 GPR63
GPR64 GPR65 GPR68 GPR75 GPR78 GPR79 GPR82
GPR83 GPR84 GPR85 GPR87 GPR88 GPR97 GPR98
GPS1 GRAP2 GRB10 GRB14 GRB2 GRB7 GRK1
GRK4 GRK5 GRK6 GRK7 GRM7 GRP GRWD1
GSTM1 GSTM3 GSTP1 GSTT1 GUCY2F H1FX H2AFX
HADHB HBA1 HCFC1 HCK HCL1 HCL2 HCL3
HDAC6 HEATR2 HEATR3 HEXIM1 HGF HGS HIF1A
HIST1H1A HIST1H1E HIST1H1T HIST1H2AA HIST1H2BD HIST1H2BH HIST1H3A
HIST1H3B HIST1H3C HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H
HIST1H3I HIST1H3J HIST1H4A HIST2H2AA3 HIST2H2AA4 HIST3H3 HLA-A
HLA-B HNRNPA1 HNRNPA2B1 HNRNPAB HNRNPF HNRNPH1 HNRNPH2
HNRNPK HNRNPM HNRNPU HOOK2 HOXA9 HOXC10 HRAS
HRG HSD17B12 HSP90AA1 HSP90AB1 HSP90B1 HSPA1A HSPA1L
HSPA2 HSPA4 HSPA5 HSPA8 HSPA9 HSPB1 HSPD1
HSPG2 HTRA1 IARS ICAM1 ICR1 ICR3 ICR4
ICR5 IFI27 IFI44 IFNA1 IFNA10 IFNA13 IFNA14
IFNA16 IFNA17 IFNA2 IFNA21 IFNA4 IFNA5 IFNA6
IFNA7 IFNA8 IFNG IGF1 IGF2 IGFBP3 IL13
IL17A IL1A IL1B IL33 IL4 IL4R IL6
IL8 ILF3 ILVBL IMPDH2 IMPG2 INS INSR
INSRR IPCEF1 IPO11 IPO13 IPO4 IPO5 IPO8
IPO9 IQGAP3 IQSEC1 IRF1 IRF6 IRS1 IRS2
IRS4 ITCH ITGA1 ITGA10 ITGA11 ITGA2 ITGA3
ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGB4
ITIH2 ITLN1 ITPR3 ITSN1 ITSN2 JAK1 JAK2
JAK3 JUN JUP KCTD12 KCTD16 KCTD8 KCTD9
KDELR2 KDR KIAA1244 KIAA1524 KITLG KPNA1 KPNB1
KRAS KRT10 KRT14 KRT17 KRT19 KRT5 KRT6A
KRT8 L1CAM LAMP1 LANCL2 LDLRAP1 LEP LGALS3
LGALS8 LHCGR LILRB1 LIMA1 LIN7C LMNA LMO7
LOXL4 LPA LPAR1 LPAR2 LPAR3 LPP LRIG1
LRIG3 LRP1 LRP2 LRP5 LRP6 LRPPRC LRRC59
LRRFIP2 LRSAM1 LTN1 LUC7L2 LUZP1 MAP1LC3A MAP2K1
MAP3K12 MAP3K14 MAP3K7 MAP4K1 MAPK8IP1 MAPK8IP2 MARS
MARVELD2 MASP1 MAST1 MATK MATR3 MCL1 MCM5
MDH1 MEA1 MEGF6 MET MGARP MGST1 MIF
MMP1 MMP10 MMP11 MMP12 MMP13 MMP14 MMP15
MMP16 MMP17 MMP19 MMP2 MMP20 MMP21 MMP24
MMP25 MMP26 MMP27 MMP28 MMP3 MMP7 MMP8
MMS19 MOB4 MON2 MPRIP MPV17 MRPS14 MRPS17
MRPS18B MRPS22 MRPS23 MRPS25 MRPS26 MRPS27 MRPS28
MRPS34 MRXS5 MT-CO2 MTNR1A MTOR MTTP MUC1
MUC12 MUC13 MUC15 MUC16 MUC17 MUC19 MUC2
MUC20 MUC21 MUC22 MUC4 MUC5AC MUC6 MUC7
MUC8 MYCBP MYH10 MYH14 MYH9 MYL12A MYL12B
MYL6 MYL9 MYLIP MYO1A MYO1B MYO1C MYO3B
MYO6 NA NANOG NBEAL2 NCAPG2 NCAPH2 NCDN
NCK1 NCK2 NCL NCOA3 NDFIP1 NDFIP2 NDN
NDUFA4 NECAP2 NEDD4L NEDD8 NEFH NELL1 NEU3
NEXN NFKB1 NGF NLRP10 NONO NOS2 NOS3
NOTCH1 NOTCH2 NOTCH3 NOTCH4 NOX1 NOX3 NOX4
NOX5 NPM1 NPR1 NPY4R NPY6R NQO2 NRAS
NRG1 NRG2 NTRK2 NUMB NUMBL NUP43 NUP85
NUP93 NXPE2 OAZ1 ODF3L2 OGDH OLFM1 OPN1LW
OS9 OTUD7B P2RX2 P2RY2 P4HB PABPC1 PAEP
PAG1 PAK1 PAK4 PARK2 PAWR PCMT1 PCNA
PDCD6IP PDGFA PDGFC PDGFD PDGFRB PDIA3 PDK1
PDK3 PDLIM7 PEX19 PFKL PFKP PGF PHB2
PHGDH PHKA2 PHLDA1 PI3 PICALM PIGR PIK3C2A
PIK3C2G PIK3CB PIK3CD PIK3CG PIK3R2 PIK3R3 PIK3R5
PIN4 PITPNA PKD1L3 PKDREJ PKIA PKM PKP2
PLA2G4A PLA2R1 PLAA PLAU PLAUR PLCG1 PLCH1
PLD1 PLD2 PLD3 PLD4 PLD5 PLD6 PLEKHA6
PLG PLS3 PLSCR1 PNPLA2 POLDIP2 PON2 POTEKP
POU5F1 PPARA PPARG PPIA PPP1CB PPP1R12A PPP1R9B
PPP2CB PPP2R1B PPP2R2A PPP2R3A PPP2R5E PPP3CA PPP5C
PPP6C PPP6R1 PPP6R3 PRCC PRDX1 PRDX2 PREX1
PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKACA PRKACB PRKACG
PRKAG1 PRKAG2 PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA
PRKCB1 PRKCD PRKD1 PRKDC PRL PRMT5 PRSS12
PRSS3 PSMA7 PSMD2 PSMD4 PTAFR PTBP1 PTCD3
PTEN PTGDS PTH PTH1R PTHLH PTK2 PTK2B
PTK6 PTK7 PTPLAD1 PTPN1 PTPN11 PTPN12 PTPN2
PTPN23 PTPN6 PTPRA PTPRB PTPRC PTPRD PTPRF
PTPRJ PTPRK PTPRS PTRF PTTG1 PXN RAB3A
RAB7A RABGEF1 RAC1 RAC2 RAC3 RACGAP1 RAE1
RAF1 RAMP1 RAMP2 RANBP1 RANGAP1 RAP1GAP RAP1GDS1
RAP2B RAPGEF1 RARS RASA1 RASA2 RASA3 RASGRP3
RBBP7 RBCK1 RBL2 RBM10 RBM25 RBM41 RCC2
RCN2 REG1A RELA REPS1 RET RGS16 RHO
RHOB RIN1 RIN2 RIOK1 RIPK1 RNF115 RNF126
RNF213 RNF41 RNMT ROCK1 ROCK2 ROR1 ROS1
RPL10 RPL12 RPL17 RPL18 RPL18A RPL21 RPL23
RPL23A RPL24 RPL26 RPL27 RPL27A RPL3 RPL30
RPL31 RPL35A RPL36 RPL4 RPL7 RPLP2 RPN1
RPS11 RPS13 RPS14 RPS15 RPS15A RPS16 RPS18
RPS2 RPS20 RPS23 RPS25 RPS26 RPS26P11 RPS27A
RPS28 RPS3 RPS3A RPS4X RPS5 RPS8 RPS9
RUSC2 RUVBL1 RUVBL2 RXRA S100A10 S100A11 S100A14
S100A16 S100A2 S100A6 S100A7 S100A8 S100A9 SAAL1
SAFB2 SCAMP3 SCIN SDC3 SEC13 SEC14L2 SEC61A1
SEL1L SEPP1 SERAC1 SERPINB4 SERPINE1 SERPINH1 SETD2
SFN SFPQ SGK1 SGPL1 SGSM2 SH2B1 SH2B3
SH2D1A SH2D2A SH2D3A SH3BGRL SH3BGRL3 SH3D21 SH3GL1
SH3GL3 SH3GLB2 SH3KBP1 SHC1 SHC2 SHC3 SHC4
SHMT2 SIRPA SLA SLA2 SLC22A3 SLC25A1 SLC25A3
SLC25A4 SLC25A5 SLC39A11 SLC39A7 SLC3A2 SLC5A1 SLC7A5
SLIRP SLITRK5 SMARCA5 SMC2 SMU1 SMURF1 SMURF2
SNAP25 SNRPD1 SNRPD2 SNX1 SNX6 SNX9 SOAT1
SOCS1 SOCS4 SOCS7 SORBS2 SOS1 SP1 SP3
SPCS2 SPECC1 SPECC1L SPRR1A SPRY1 SPRY2 SPRY3
SPRY4 SPSB1 SPTAN1 SPTBN1 SPTBN4 SPTLC1 SRP14
SRP9 SRSF10 SSBP1 SSR1 STAM STAM2 STAT3
STAT5A STAT5B STIP1 STRAP STUB1 SUSD1 SVIL
SYN1 SYNGAP1 SYNPO SYP TANK TAOK2 TARBP2
TAS1R2 TAT TBRG4 TCF12 TCF15 TCF19 TCF20
TCF21 TCF23 TCF24 TCF25 TCF3 TCF4 TCF7
TECR TELO2 TFAP2A TFF1 TFF3 TGFA TGFB1
TGFB2 TGFB3 TGFBR2 THADA THEM6 THRAP3 TIAF1
TIMM21 TIMM50 TJP1 TLR4 TLR7 TMCO3 TMED7
TMEM33 TMOD3 TNC TNF TNFAIP2 TNFSF10 TNK2
TNPO1 TNPO2 TNPO3 TNS3 TNS4 TOM1L1 TOM1L2
TOP2A TOR4A TP53 TP63 TPI1 TPM1 TPM2
TPP1 TPT1 TRADD TRAF1 TRAF2 TRAF3 TRAF4
TRAF5 TRAF6 TRAF7 TRAPPC3 TRIM29 TRPC4 TRPV1
TTC27 TTI1 TTI2 TUBA1A TUBA1B TUBA4A TUBB
TUBB2A TUBB3 TUBB4A TUBB4B TUBB6 TUFM TWIST1
TXN TYR TYRP1 UACA UBASH3A UBASH3B UBB
UBC UBE2D1 UBE2D2 UBE2D3 UBE2V2 UBE4B UCHL1
UGDH UROD USP6NL USP8 USP9X UTP15 UTP18
UTP20 UTP23 UTP3 UTP6 VAC14 VAPA VAPB
VAV1 VAV3 VCAM1 VEGFA VEGFB VIM VIP
VIPR1 VLDLR VPS13A VPS33B WDR1 WDR26 WNT1
WNT11 WNT16 WNT2 WNT3 WNT4 WNT6 WT1
XPO1 XPO4 XPO5 XPO6 XPO7 XPOT XRCC5
XRCC6 XRN2 YAP1 YBX1 YES1 YTHDF1 YWHAB
YWHAE YWHAG YWHAH YWHAQ YWHAZ ZAP70 ZFYVE20
ZFYVE28 ZGLP1 ZPR1 ZW10
Data information
Please see the Gene Interactions Track Manual.