Gene interactions and pathways from curated databases and text-mining
MAPK4: top 25 interacting genes (chr18:48086456-48258196)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only MAPK4-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
Gene:               Hide non-MAPK4 interactions     Show top Genes on graph    

Less-frequently mentioned interactions with MAPK4, not among the Top 25
Other genes interacting with MAPK4. Mouse-over to show number of abstracts or databases. Sorted alphabetically (sort by article count).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

A2M AANAT ABCB1 ABCC1 ABL1 ACD ADAM11
ADAM17 ADAMTS4 ADCY1 ADCY10 ADCY2 ADCY3 ADCY4
ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADCYAP1 ADM
ADORA1 ADORA3 ADRBK1 AGO2 AGTR1 AGTR2 AIRE
AJUBA AKT1S1 AKTIP ALB ALOX5 ANG ANGPT1
ANGPT2 ANGPT4 ANGPTL1 ANXA1 ANXA5 ANXA6 APC
APOB APOE APP APPL1 AQP1 AQP2 AR
AREG ARG1 ARG2 ARHGEF1 ARSA ARSK ASIP
ATF1 ATF2 ATF3 ATF4 ATF5 ATF6 ATF7
ATP1A1 ATP5O ATR AVP BAD BANF1 BAX
BCL10 BCL2 BCL3 BCL5 BCL6 BCL9 BCR
BDNF BGN BID BMP1 BMP10 BMP15 BMP2
BMP3 BMP4 BMP5 BMP6 BMP7 BRAF BSG
BTRC C19orf80 C1orf228 CA1 CA2 CADM1 CALM1
CALM2 CALM3 CANX CAPN1 CAPN10 CAPN11 CAPN12
CAPN13 CAPN14 CAPN15 CAPN2 CAPN3 CAPN5 CAPN6
CAPN7 CAPN8 CAPN9 CASC3 CASP1 CASP10 CASP12
CASP14 CASP16 CASP2 CASP3 CASP4 CASP5 CASP6
CASP7 CASP8 CASP9 CAT CAV1 CAV2 CAV3
CBL CCK CCL11 CCL17 CCL2 CCL20 CCL24
CCL3 CCL4 CCL5 CCNB1 CCNC CCND1 CCND3
CCR2 CCR5 CCR7 CD2 CD24 CD28 CD36
CD38 CD4 CD40 CD40LG CD44 CD46 CD55
CD69 CD79A CD79B CD86 CDC16 CDC20 CDC23
CDC26 CDC27 CDC37 CDC42 CDC6 CDC73 CDH1
CDH10 CDH11 CDH12 CDH13 CDH15 CDH16 CDH17
CDH18 CDH19 CDH2 CDH20 CDH22 CDH23 CDH24
CDH26 CDH3 CDH4 CDH5 CDH6 CDH7 CDH8
CDH9 CDK1 CDK2 CDK4 CDK8 CDKN1A CDO1
CEBPA CEBPB CEBPD CEP104 CEP112 CEP120 CEP128
CEP135 CEP152 CEP164 CEP170 CEP19 CEP192 CEP250
CEP290 CEP350 CEP41 CEP44 CEP55 CEP57 CEP63
CEP68 CEP70 CEP72 CEP76 CEP78 CEP85 CEP89
CEP95 CEP97 CFLAR CFTR CHGA CHI3L1 CHKA
CHUK CIITA CISH CLDN18 CLU CNR1 CNR2
CNTF CPA1 CPE CPOX CR1 CREB1 CREB3
CREB5 CRH CRK CRP CSE CSF1 CSF1R
CSF2 CSF3 CSK CSNK2B CSRP1 CTGF CTNNB1
CTNNBL1 CTNND1 CTR9 CUL1 CUL5 CX3CL1 CX3CR1
CXADR CXCL1 CXCL10 CXCL11 CXCL12 CXCL13 CXCL14
CXCL16 CXCL17 CXCL2 CXCL3 CXCL5 CXCL6 CXCL9
CXCR1 CXCR2 CXCR4 CYP19A1 CYP24A1 CYP2E1 CYP3A
DAB2 DDIT3 DDR1 DDT DES DIANPH DISC1
DISC2 DNM1 DOK1 DOK4 DOK5 DRG1 DRG2
DST DUSP1 DUSP10 DUSP11 DUSP12 DUSP13 DUSP14
DUSP15 DUSP16 DUSP18 DUSP19 DUSP2 DUSP21 DUSP22
DUSP23 DUSP26 DUSP27 DUSP28 DUSP3 DUSP4 DUSP5
DUSP6 DUSP7 DUSP8 DUSP9 DYNLRB1 ECM1 ECM2
EDN1 EDN2 EDN3 EDNRA EDNRB EFNA1 EFNB3
EGR1 EGR2 EGR4 EHMT1 EIF2AK2 EIF4E EIF4EBP1
ELAVL1 ELK1 EMD EPHA1 EPHA10 EPHA2 EPHA3
EPHA4 EPHA5 EPHA6 EPHA7 EPHA8 EPHB1 EPO
EPX ERBB2 ERBB2IP ERBB3 ERBB4 ERC1 ERCC1
ERVK-6 ESAT ESR1 ESR2 ETS1 ETS2 EYA1
EYA2 EYA3 EYA4 EZR F2R F2RL1 FAM57A
FAM83B FAS FASLG FASTKD5 FBXO32 FCER2 FCGR2B
FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16
FGF17 FGF18 FGF19 FGF20 FGF21 FGF22 FGF23
FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9
FGFR1 FGFR2 FGFR3 FGFR4 FLNA FLT3 FOS
FOSL1 FOSL2 FRS2 FSHB FST FUT4 FYN
GAB1 GAB2 GAL GAPDH GAS6 GAST GATA1
GATA3 GATA4 GDF15 GDF5 GDNF GFAP GH1
GHR GHRH GHSR GIP GJA1 GJC1 GJC2
GJC3 GLI1 GNA12 GNA13 GNAI1 GNAI2 GNAI3
GNRH1 GNRH2 GNRHR GP2 GP5 GP6 GP9
GPER1 GPI GPR1 GPR101 GPR107 GPR108 GPR110
GPR111 GPR112 GPR113 GPR114 GPR115 GPR116 GPR119
GPR12 GPR123 GPR124 GPR125 GPR126 GPR128 GPR132
GPR133 GPR135 GPR137 GPR139 GPR141 GPR142 GPR143
GPR144 GPR146 GPR148 GPR149 GPR15 GPR150 GPR151
GPR152 GPR153 GPR155 GPR156 GPR157 GPR158 GPR160
GPR161 GPR162 GPR17 GPR171 GPR173 GPR174 GPR176
GPR179 GPR18 GPR180 GPR182 GPR183 GPR19 GPR20
GPR21 GPR22 GPR25 GPR26 GPR27 GPR3 GPR31
GPR32 GPR33 GPR34 GPR35 GPR36 GPR37 GPR39
GPR4 GPR42 GPR45 GPR50 GPR52 GPR55 GPR56
GPR6 GPR61 GPR62 GPR63 GPR64 GPR65 GPR68
GPR75 GPR78 GPR79 GPR82 GPR83 GPR84 GPR85
GPR87 GPR88 GPR97 GPR98 GRB10 GRB2 GRK1
GRK4 GRK5 GRK6 GRK7 GRP GSK3B HABP2
HBEGF HCL1 HCL2 HCL3 HDAC1 HDAC2 HDAC3
HGF HIF1A HLA-DRB1 HMGB1 HMOX1 HNF1B HNRNPF
HNRNPH1 HNRNPK HRAS HRG HRH1 HSD11B2 HSP90AA1
HSP90AB1 HSPA5 HSPB1 HSPD1 HSPG2 HTR1A HTR2A
ICAM1 IDO1 IFI27 IFI44 IFNB1 IFNG IGF1R
IGF2 IGFBP1 IGFBP3 IGFBP5 IHH IKBKB IKBKG
IL10 IL11 IL12A IL12B IL13 IL15 IL16
IL17A IL17D IL17F IL17RD IL18 IL19 IL1A
IL1RN IL2 IL20 IL21 IL22 IL23A IL24
IL25 IL26 IL27 IL2RB IL3 IL31 IL32
IL33 IL34 IL37 IL4 IL5 IL6ST IL7
IL9 ILK INPPL1 INSR IRAK1 IRAK2 IRAK3
IRAK4 IRF1 IRS1 ITGA5 ITGAM ITGAV ITGB1
ITGB2 ITIH4 JAK1 JAK2 JAK3 JUNB KANK2
KCNH4 KCNH8 KDR KITLG KLF5 KMT2D KRAS
KSR1 LANCL1 LCK LDLR LEO1 LEP LGALS1
LIF LIFR LOX LPA LRP1 LRPAP1 LRPPRC
LTA LTB LTF LYN MADD MAFA MAP2K1
MAP2K2 MAP2K3 MAP2K4 MAP2K5 MAP2K6 MAP2K7 MAP3K1
MAP3K10 MAP3K11 MAP3K12 MAP3K13 MAP3K14 MAP3K2 MAP3K3
MAP3K4 MAP3K5 MAP3K7 MAP3K8 MAPK1 MAPK3 MAPKAPK2
MAPKAPK3 MAPKAPK5 MATK MBP MC1R MCL1 MDM2
MED1 MED12 MED13 MED14 MED17 MED21 MED24
MED4 MED6 MEF2C MEFV MET MIF MIP
MIPEP MITF MLST8 MMP1 MMP10 MMP11 MMP12
MMP13 MMP14 MMP15 MMP16 MMP17 MMP19 MMP2
MMP20 MMP21 MMP24 MMP25 MMP26 MMP27 MMP28
MMP3 MMP7 MMP8 MMP9 MNAT1 MOCOS MOK
MOS MPZ MRE11A MRXS5 MSH2 MSH3 MSH4
MSH5 MSH6 MSK10 MSK32 MSK38 MSK9 MST1
MST1R MT4 MTOR MUC1 MUC12 MUC13 MUC15
MUC16 MUC17 MUC19 MUC2 MUC20 MUC21 MUC22
MUC4 MUC5AC MUC5B MUC6 MUC7 MUC8 MYC
MYD88 MYH1 MYH10 MYH11 MYH13 MYH14 MYH15
MYH16 MYH2 MYH3 MYH4 MYH6 MYH7 MYH8
MYH9 MYL9 MYLIP MYLK NA NAALADL1 NAMPT
NCAM1 NCAM2 NCF1 NCF2 NEU1 NEU3 NEUROD1
NEUROD2 NEUROD4 NEUROD6 NF1 NF2 NFATC1 NFKBIA
NGF NOD1 NODAL NOS1 NOS3 NOTCH1 NOTCH2
NOTCH3 NOTCH4 NOX1 NOX3 NOX4 NOX5 NPB
NPPA NPR3 NPS NPY NPY2R NPY4R NPY6R
NR2C2 NR4A1 NRAS NRG1 NRG2 NRG3 NRG4
NRP1 NTF3 NTF4 NTRK1 NTRK2 NTRK3 NTS
NUP43 OCLN ODC1 OLR1 OPRM1 OSM P2RX4
P2RX7 P2RY2 PAEP PAF1 PAK1 PAK2 PAK3
PAK4 PAK6 PAK7 PAM PAN2 PAN3 PARP1
PARP10 PARP11 PARP12 PARP14 PARP15 PARP16 PARP2
PARP3 PARP4 PARP6 PARP8 PARP9 PAX6 PCK2
PCNA PDCD11 PDGFA PDGFB PDGFRB PDK1 PDLIM7
PEBP1 PFKP PGD PGF PGR PHKA2 PI3
PIGR PIK3C3 PIK3CA PIK3CG PIK3R1 PIK3R4 PIM1
PKD2 PLA2G1B PLA2G4A PLAT PLAU PLAUR PLCB1
PLCB2 PLCB3 PLCB4 PLCG1 PLCG2 PLD1 PLD2
PLD3 PLD4 PLD5 PLD6 PLG PLXNB1 POT1
PPARA PPARD PPARG PPARGC1A PPP2CA PPP2R1A PPP2R2B
PPP3CA PPP3CB PPP3CC PPP3R1 PPP5C PRDX2 PRDX6
PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKACB PRKACG PRKAG1
PRKAG2 PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCB
PRKCD PRKCE PRKD1 PRL PROK1 PRTN3 PRX
PSEN1 PSIP1 PSMA7 PSMG1 PTBP1 PTBP2 PTCH1
PTEN PTGES PTH PTH1R PTHLH PTK2 PTK2B
PTK6 PTK7 PTPN1 PTPN11 PTPN22 PTPN5 PTPN6
PTS PTTG1 PTTG2 PTX3 PTX4 PXN QRICH1
QRICH2 RABEPK RAC1 RAC2 RAC3 RAD50 RAD51
RAF1 RARA RASA1 RASGRF1 RASGRF2 RASGRP1 RB1
RBBP4 RBBP7 RBL1 RBL2 REG1A RENBP RET
RETN RGS3 RGS4 RHO RHOA RIPK2 RIT1
ROCK1 ROCK2 RPS27 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA4
RPS6KA5 RPS6KA6 RPS6KB1 RPTOR RRAD RRAS RUNX2
S100A12 S100A8 S100A9 S100B SAA1 SCARB1 SCNN1A
SDS SELE SELL SELP SEPP1 SERPINC1 SERPINE1
SERPINF1 SETD2 SFN SFTPC SGK1 SHC1 SHH
SIRPA SIRT1 SKP1 SLC12A3 SLC22A3 SLC25A3 SLC2A4
SLC33A1 SLC9A1 SLCO6A1 SLPI SMAD1 SMAD2 SMAD3
SMAD4 SMAD5 SMAD6 SMAD7 SMAD9 SMC2 SMC3
SMC4 SMC5 SMC6 SMG1 SMN1 SMPD3 SMURF1
SNAP25 SOAT1 SOCS1 SOCS3 SOD1 SOD2 SOD3
SOS1 SOS2 SOX9 SP1 SP3 SPAG8 SPARC
SPHK1 SPP1 SPRED1 SPRY2 SRC SREBF1 SRF
SRPK1 SRY SST ST3GAL4 STAR STAT1 STAT3
STAT5A STAT6 SULT1E1 SYK SYN1 SYN2 SYN3
SYT1 TAB1 TAB2 TAC1 TAC3 TAC4 TAF1
TAF6 TAF9 TANK TAS2R38 TAT TCF12 TCF15
TCF19 TCF20 TCF21 TCF23 TCF24 TCF25 TCF3
TCF4 TCF7 TERF1 TERF2 TERF2IP TFRC TGFA
TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR2 TIE1 TIMP1
TIMP2 TIMP3 TINF2 TLR1 TLR10 TLR2 TLR3
TLR4 TLR5 TLR6 TLR7 TLR8 TLR9 TMED7
TNFRSF11B TNFRSF1A TNFRSF9 TNFSF10 TNFSF11 TNFSF12 TNPO1
TP53 TPH1 TPO TRADD TRAF1 TRAF2 TRAF3
TRAF4 TRAF5 TRAF6 TRAF7 TRH TRO TSC22D3
TWIST1 TXN TXNIP TYR UBC UCN UCP1
UTP15 UTP18 UTP20 UTP23 UTP3 UTP6 UTS2
VAV1 VCAM1 VCP VDR VEGFC VIP VWF
WAS WDR61 WNK1 WNT1 WNT11 WNT16 WNT2
WNT3 WNT4 WNT6 XCL1 XIAP XRCC5 XRCC6
YME1L1 YWHAB ZAP70 ZFP36 ZGLP1
Data information
Please see the Gene Interactions Track Manual.