Gene interactions and pathways from curated databases and text-mining
IRS1: top 25 interacting genes (chr2:227596027-227664536)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only IRS1-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
Gene:               Hide non-IRS1 interactions     Show top Genes on graph    

Less-frequently mentioned interactions with IRS1, not among the Top 25
Other genes interacting with IRS1. Mouse-over to show number of abstracts or databases. Sorted alphabetically (sort by article count).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

AKT1S1 ANG ANGPT2 ANXA6 AP3S1 APP ARF6
ARG1 ARG2 ATP2A1 ATP2A2 ATXN2L BCAR1 BCL2L1
BUB3 C1orf116 CASP1 CASP10 CASP12 CASP14 CASP16
CASP2 CASP3 CASP4 CASP5 CASP6 CASP7 CASP8
CASP9 CAST CAV1 CAV3 CBL CBLB CCND1
CDH1 CDK11A CHD8 CHUK CISH CRP CSF1R
CSNK1D CSNK2A1 CSNK2B CTNNB1 CYTH2 CYTH3 DCAF7
DDR1 DHX8 DNAJA2 DOCK9 DOK1 DYRK1A EGF
EGFR EGR1 EIF4E EPB41L5 EPHA2 ERBB2 ERBB2IP
ERBB3 ESR1 FAM83G FBXO25 FBXW8 FES FGF21
FGFR1 FGFR2 FGFR4 FGR FLT1 FLT4 FN1
FOXO1 GAB1 GDNF GFRA1 GH1 GH2 GHR
GNB2L1 GRB10 GRB2 GRK1 GRK4 GRK5 GRK6
GRK7 GSK3A GSK3B HRAS HSPA1A IARS IFNG
IGF1R IGFBP3 IKBKB IKBKG IL15 IL2 IL2RA
IL2RB IL2RG IL4 IL4R IL6 IL7 IL8
INPP5D IRF5 IRS2 IRS4 ITGAV ITGB1 ITGB3
ITGB4 JAK1 JAK2 JUN KDR KHDRBS1 KIT
KRAS LCK LEMD3 LEPR LRCH1 MAP2K1 MAPK7
MAPK8 MAPK9 MET MLST8 MYLIP NCK2 NEDD4
NFKB1 NGF NGFR NISCH NOS1 NOS2 NOS3
NPM1 NRAS NTRK2 NTRK3 OPA1 PABPC1 PDPK1
PHIP PIK3C2A PIK3C2B PIK3C2G PIK3CB PIK3CD PIK3CG
PIK3IP1 PIK3R2 PIK3R3 PIK3R5 PJA1 PLCG2 POLDIP2
PPARG PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B
PRKCA PRKCE PRKCG PRKCQ PRKCZ PRKD1 PRL
PSPC1 PTBP1 PTEN PTK2 PTPN1 PTPN11 PTPN6
PTPRC PTPRF PTPRU PXN RAB11FIP5 RAD51 RAF1
RASA1 RELA RET RETN RPL3 RPL4 RPS6KB1
RPTOR RRAD SFN SGK1 SGK2 SGK3 SH2B1
SH2B2 SH2B3 SHC1 SHC2 SHC3 SIK2 SIK3
SIRT1 SLC25A12 SLC2A4 SLC9A3R2 SMAD2 SMAD3 SMAD4
SMURF2 SNW1 SOCS1 SOCS2 SOCS3 SOCS4 SORBS1
SQRDL STAT5A TCP1 TEK TRIM72 TUB TYR
U2AF2 UBC UBTF UCP1 USP7 VAV2 VEGFA
WWP2 YTHDF2 YWHAB YWHAE YWHAG YWHAH YWHAZ
YY1 ZFYVE9
Data information
Please see the Gene Interactions Track Manual.