Gene interactions and pathways from curated databases and text-mining
TLR4: top 25 interacting genes (chr9:120466680-120487013)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only TLR4-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with TLR4, not among the Top 25
Other genes interacting with TLR4. Mouse-over to show number of abstracts or databases. Sorted alphabetically (sort by article count).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

ADAM11 AGTR1 AHSA1 AKT1 AKT2 AKT3 ANG
ANGPT2 ANPEP ANXA6 APC APCS APOB APOE
ARAF ARSK BCR BGN BIRC2 BIRC3 BMP1
BMP2 BPI BTK C1QA C1QB C1orf228 CASP1
CASP10 CASP12 CASP14 CASP16 CASP2 CASP3 CASP4
CASP5 CASP6 CASP7 CASP8 CASP9 CCDC47 CCL2
CCL3 CCL5 CCNG1 CCR7 CD14 CD274 CD276
CD36 CD4 CD40 CD69 CD79A CD80 CD83
CD86 CD8A CD8B CDC73 CHUK CISH CLEC7A
CNPY4 CPOX CRK CSE CSF1 CSF2 CSRP1
CTR9 CTSK CXCL1 CXCL10 CXCL11 CXCL12 CXCL13
CXCL14 CXCL16 CXCL17 CXCL2 CXCL3 CXCL5 CXCL6
CXCL8 CXCL9 CXCR2 DAP DEFB103B DEFB4B DES
DUSP1 EGFR EHHADH EIF2AK2 EPHB2 ESAT ETS2
F2R F2RL1 FCER2 FGB FLT3LG FOS FOXP3
GAL GATA1 GIF GPI GRAP2 GRK5 HBD
HGS HIF1A HLA-DRA HLA-DRB1 HMGB1 HMGB2 HMGB3
HMGB4 HMOX1 HSP90B1 HSPA4 HSPA8 HSPA9 HSPB3
HSPD1 IBD2 IBD3 IBD4 IBD5 IBD6 IBD7
IBD8 IBD9 ICAM1 IDO1 IFN1@ IFNAR1 IFNB1
IKBKB IKBKG IL11 IL13 IL15 IL16 IL17A
IL17D IL18 IL19 IL1A IL1B IL1R1 IL2
IL20 IL21 IL22 IL23A IL24 IL25 IL26
IL27 IL2RA IL3 IL31 IL32 IL33 IL34
IL37 IL4 IL5 IL7 IL9 INS IRAK1
IRAK2 IRAK3 IRAK4 IRF1 IRF2 IRF3 IRF4
IRF5 IRF7 IRF8 IRF9 ITGAM JAG1 JAK1
JAK2 JAK3 JUN KLK3 KLRC1 LANCL1 LBP
LCN2 LEO1 LEP LRRK2 LTA LTN1 MAP3K1
MAP3K7 MAP4K4 MAPK4 MAPK6 MAPK7 MAPK8 MAPK8IP3
MAPK9 MBL2 MIF MIP MIPEP MKL1 MMP1
MMP10 MMP11 MMP12 MMP13 MMP14 MMP15 MMP16
MMP17 MMP19 MMP2 MMP20 MMP21 MMP24 MMP25
MMP26 MMP27 MMP28 MMP3 MMP7 MMP8 MMP9
MOCOS MPO MSC MTOR MYLIP NAALADL1 NCF1
NEU1 NF1 NFKBIA NFKBIZ NGF NM NOD2
NOS1 NOS2 NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4
NOX1 NOX3 NOX4 NOX5 NR0B1 NTF3 NUP153
NUP210 NUP214 NUP62 OLR1 PAF1 PAM PDC
PDCD11 PDS5A PECAM1 PI3 PIK3CA PIK3CD PIK3R1
POLDIP2 PPARG PPP4C PRDM1 PRDX2 PRKCA PRKCZ
PTGS2 PTX3 PTX4 QRICH1 QRICH2 RAB7B RABEPK
RAC1 RANBP2 REL RETN RHOA RIPK1 RIPK2
RIPK3 RNF19A RNF216 RPS27A RPTOR S100A8 SAA1
SAMHD1 SARM1 SELE SELL SERTAD1 SETD2 SFTPA1
SFTPA2 SFTPD SIGIRR SIRPA SLC22A3 SMAD3 SNRNP200
SOAT1 SOCS1 SOCS2 SOCS3 SPP1 SRC STAT1
STAT3 STK11IP STUB1 SULT2A1 SYK SYT1 TAB1
TAB2 TAB3 TBCE TBK1 TCF12 TCF15 TCF19
TCF20 TCF21 TCF23 TCF24 TCF25 TCF3 TCF4
TCF7 TGFB1 TGFB2 TGFB3 TICAM1 TICAM2 TIFA
TIRAP TLR1 TLR10 TLR3 TLR5 TLR6 TLR7
TLR8 TLR9 TNC TNFSF13B TOLLIP TP53 TP63
TRADD TRAF3 TRAF6 TRAM1 TRAM2 TREM1 TREM2
TRIL TRIM69 TSLP UBA52 UBB UBC UBE2D1
UBE2D2 UBE2D3 UBE2N UBE2NL UBE2V1 UBR1 UBR2
UMOD VCAM1 VDR VEGFA VIP WDR61 WNT1
WNT11 WNT16 WNT2 WNT3 WNT4 WNT6 XBP1
ZNF160
Data information
Please see the Gene Interactions Track Manual.