This directory contains download files of the Saccharomyces cerevisiae genome sequence and associated annotations. The data is based on sequence dated 1 Oct. 2003 in the Saccharomyces Genome Database (http://www.yeastgenome.org/) and was obtained from the site ftp://genome-ftp.stanford.edu/pub/yeast/data_download. The S288C strain was used in this sequencing project. Files included in this directory: sacCer1.2bit - contains the complete S. cerevisiae/sacCer1 genome sequence in the 2bit file format. While we are providing the .2bit for this assembly, we will continue to use the .nib files in the Genome Browser. No masking has been applied to these sequences. The utility program, twoBitToFa (available from the kent src tree), can be used to extract .fa file(s) from this file. A pre-compiled version of the command line tool can be found at: http://hgdownload.cse.ucsc.edu/admin/exe/linux.x86_64/ See also: http://genome.ucsc.edu/admin/git.html http://genome.ucsc.edu/admin/jk-install.html chromFa.zip - The working draft sequence in one file per chromosome. (No masking of repetitive sequences.) est.fa.gz - Yeast EST sequences deposited into GenBank. mrna.zip - Yeast mRNA from GenBank. multizYeast.zip - Multiple alignments done with Webb Miller's multiz program on seven species of Saccharomyces in .maf format. For a description of the multiple alignment format (MAF), see http://genome.ucsc.edu/goldenPath/help/maf.html. sacCer1.chrom.sizes - Two-column tab-separated text file containing assembly sequence names and sizes. ----------------------------------------------------------------- If you plan to download a large file or multiple files from this directory, we recommend that you use ftp rather than downloading the files via our website. To do so, ftp to hgdownload.cse.ucsc.edu, then go to the directory goldenPath/sacCer1/bigZips. To download multiple files, use the "mget" command: mget ... - or - mget -a (to download all the files in the directory) All the tables in this directory are freely available for public use.