This directory contains the Mar. 2006 chromosome-based chimpanzee assembly produced by Washington University, St. Louis. It is based on the Oct. 2005 6X draft assembly (Build 2 Version 1), produced by the Chimpanzee Genome Sequencing Consortium. The whole genome shotgun sequence data were assembled using PCAP by the Washington University Genome Sequencing Center. The underlying whole genome shotgun data were generated at the Washington University School of Medicine and the Broad Institute. A 5-megabase region of chromosome 7 was finished at the Washington University Genome Sequencing Center (chr7:84674857-89461887). The chromosome Y sequence was finished at the Washington University Genome Sequencing Center with detailed mapping and extensive collaboration with the Broad Institute. This assembly also contains finished chromosome 21 sequence from the Riken Genome Sciences Center. Files included in this directory: - chr*.fa.zip: compressed FASTA sequence of each chromosome. Each chromosome is in a separate file in a zipped Fasta format. Repeats -- which are shown in lower case -- are annotated by RepeatMasker run at the sensitive setting. The RepeatMasker version used was: 1.11 2006/01/20 (open 3-1-3) The RepeatMasker pan_troglodytes library was used, with the addition of 2 subtelomeric satellite repeats provided by the Evan Eichler lab. The library version used was: 20060119 Tandem repeats of period 12 or less are also masked out using Tandem Repeats Finder. The main assembly is contained in the chrN.fa files, where N is the name of the chromosome. The chrN_random.fa files contain sequence that cannot be placed with certainty at a specific place on the chromosome. ------------------------------------------------------------------- If you plan to download a large file or multiple files from this directory, we recommend that you use ftp rather than downloading the files via our website. To do so, ftp to hgdownload.cse.ucsc.edu, then go to the directory goldenPath/panTro2/chromosomes. To download multiple files, use the "mget" command: mget ... - or - mget -a (to download all the files in the directory) The chimp sequence is made freely available before scientific publication with the following understanding: 1. The data may be freely downloaded, used in analyses, and repackaged in databases. 2. Users are free to use the data in scientific papers analyzing particular genes and regions if the providers of these data are properly acknowledged. See http://genome.ucsc.edu/goldenPath/credits.html for credit information. 3. The centers producing the data reserve the right to publish the initial large-scale analyses of the data set, including large-scale identification of regions of evolutionary conservation and large-scale genomic assembly. Large-scale refers to regions with size on the order of a chromosome (that is, 30 Mb or more). 4. Any redistribution of the data should carry this notice.