This directory contains compressed phastCons scores for multiple alignments of the following assemblies to the mouse genome (Aug. 2005, mm7): - rat (rn3, Jun. 2003) - rabbit (May 2005, oryCun1) - human (May 2004, hg17) - chimp (Nov 2003, panTro1) - macaque (rheMac1) - dog (May 2005, canFam2) - cow (Mar 2005, bosTau2) - armadillo (May 2005, dasNov1) - elephant (May 2005, loxAfr1) - tenrec (Jul 2005, echTel1) - opossum (Jun 2005, monDom2) - chicken (Feb 2004, galGal2) - frog (Oct 2004, xenTro1) - zebrafish (May 2005, danRer3) - Tetraodon (Feb 2004, tetNig1) - Fugu (Aug 2002, fr1) For a description of the phastCons file format, see http://genome.ucsc.edu/goldenPath/help/phastCons.html. ----------------------------------------------------------------- If you plan to download a large file or multiple files from this directory, we recommend you use ftp rather than downloading the files via our website. To do so, ftp to hgdownload.cse.ucsc.edu, then go to the directory goldenPath/mm7/phastCons. To download multiple files, use the "mget" command: mget ... - or - mget -a (to download all the files in the directory) All files in this directory are freely available for public use. For data use restrictions regarding the other genome assemblies used in this annotation, see http://genome.ucsc.edu/goldenPath/credits.html. ------------------------------------------------------------- References for phastCons: Siepel, A., Bejerano, G., Pedersen, J.S., Hinrichs, A., Hou, M., Rosenbloom, K., Clawson, H., Spieth, J., Hillier, L.W., Richards, S., Weinstock, G.M., Wilson, R. K., Gibbs, R.A., Kent, W.J., Miller, W., and Haussler, D. Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes. Genome Res. 15, 1034-1050 (2005). (http://www.genome.org/cgi/doi/10.1101/gr.3715005) Siepel, A. and Haussler, D. Phylogenetic hidden Markov models. In Statistical Methods in Molecular Evolution (ed. Nielsen, R.) (Springer, 2005). For a discussion of the methods used to calculate the phastCons scores, see the description page for the Conservation track in the Genome Browser.