Here we show the positions of STS markers on the assembly of the working
draft genome sequence versus their positions in various maps.
July 2003 Freeze:
April 2003 Freeze:
November 2002 Freeze:
View the mapPlots for archived freezes.
These plots are described more fully in
Initial sequencing and analysis of the human genome by the International
Human Genome Sequencing Consortium,
Nature,409: 860-921, 2001. Included are the
Genethon genetic map, the
Marshfield genetic map, the
deCODE genetic map, the
GeneMap99 radiation hybrid map, the
G3 and TNG radiation hybrid maps, the
Whitehead YAC and RH maps, and the
resource of FISH-mapped BAC clones
NCBI Clone Registry).
We thank the researchers who built these maps for
making their data available.
The TNG map data is discussed in Olivier et
al., "A high resolution radiation hybrid map of the human genome draft
sequence," Science 291(5507):1298-1303, 2001, and the cytogenetic data in
of cytogenetic landmarks into the draft sequence of the human genome,"
by the BAC Resource Consortium, Nature, Vol. 409:953-958, 2001.
Data for sex-averaged
Genethon, sex-averaged Marshfield, GeneMap99 RH, G3 RH and Whitehead YAC
maps was first collected into a unified database by Greg Schuler at NCBI.
Prior to the December freeze, we also used his e-pcr program (very slightly
modified) to place the markers on the draft sequence, with the exception
of the FISH-mapped clones, which were placed by Wonhee Jang and Greg Schuler
at NCBI, with assistance from Arek Kasprzyk and Ewan Birney at EBI. Starting
with the December freeze, we began placing all markers and FISH-mapped
clones ourselves by matching the full STS sequence to the golden path whenever
possible, not just the primers. BAC ends and accession information were
also used to help place the FISH-mapped clones.