This directory contains compressed multiple alignments of the following assemblies to the human genome (hg17, May 2004): - chimp (Nov 2003, panTro1) - macaque (Jan 2006, rheMac2) - mouse (May 2004, mm7) - rat (Jun 2003, rn3) - rabbit (May 2005, oryCun1) - dog (May 2005, canFam2) - cow (Mar 2005, bosTau2) - armadillo (May 2005, dasNov1) - elephant (May 2005, loxAfr1) - tenrec (Jul 2005, echTel1) - opossum (Jun 2005, monDom2) - chicken (Feb 2004, galGal2) - frog (Oct 2004, xenTro1) - zebrafish (May 2005, danRer3) - Tetraodon (Feb 2004, tetNig1) - Fugu (Aug 2002, fr1) The chr*.maf.gz files each contain all the alignments to that particular human chromosome. The maf/upstream*.maf.gz files contain alignments in regions upstream of annotated transcription starts for RefSeq genes with annotated 5' UTRs. These files differ from the standard MAF format: they display alignments that extend from start to end of the upstream region in human, whether or not alignments actually exist. In situations where no alignments exist or the alignments of one or more species are missing, dot (".") is used as a placeholder. Multiple regions of an assembly's sequence may align to a single region in human; therefore, only the species name is displayed in the alignment data and no position information is recorded. The alignment score is always zero in these files. These files are updated weekly. For a description of multiple alignment format (MAF), see http://genome.ucsc.edu/goldenPath/help/maf.html. --------------------------------------------------------------- If you plan to download a large file or multiple files from this directory, we recommend that you use ftp rather than downloading the files via our website. To do so, ftp to hgdownload.cse.ucsc.edu, then go to the directory goldenPath/hg17/multiz17way. To download multiple files, use the "mget" command: mget ... - or - mget -a (to download all the files in the directory) All the files in this directory are freely usable for any purpose. For data use restrictions regarding the individual genome assemblies, see http://genome.ucsc.edu/goldenPath/credits.html.