This directory contains the Build 34 finished human genome assembly (hg16, Jul. 2003). The chromosomal sequences were assembled by the International Human Genome Project sequencing centers and verified by NCBI and UCSC. Files included in this directory: - chr*.fa.zip: compressed FASTA sequence of each chromosome. Each chromosome is in a separate file in a zipped Fasta format. Repeats -- which are shown in lower case -- are annotated by RepeatMasker run at the sensitive setting and Tandem Repeats Finder (repeats of period 12 or less). The main assembly is contained in the chrN.fa files, where N is the name of the chromosome. The chrN_random.fa files contain clones that are not yet finished or cannot be placed with certainty at a specific place on the chromosome. In some cases, including the human HLA region on chromosome 6, the chrN_random.fa files also contain different haplotypes from the main assembly. ------------------------------------------------------------------- If you plan to download a large file or multiple files from this directory, we recommend that you use ftp rather than downloading the files via our website. To do so, ftp to hgdownload.cse.ucsc.edu, then go to the directory goldenPath/hg16/chromosomes. To download multiple files, use the "mget" command: mget ... - or - mget -a (to download all the files in the directory) All the files in this directory are freely available for public use.