This directory contains compressed multiple alignments of the following assemblies to the D. melanogaster genome (dm3, Apr. 2006, BDGP Release 5) - D. simulans (droSim1, Apr. 2005) - D. sechellia (droSec1, Oct. 2005) - D. yakuba (droYak2, Nov. 2005) - D. erecta (droEre2, Feb. 2006) - D. ananassae (droAna3, Feb. 2006) - D. pseudoobscura (dp4, Feb. 2006) - D. persimilis (droPer1, Oct. 2005) - D. willistoni (droWil1, Feb. 2006) - D. virilis (droVir3, Feb. 2006) - D. mojavensis (droMoj3, Feb. 2006) - D. grimshawi (droGri2, Feb. 2006) - A. gambiae (anoGam1, Feb. 2003) - A. mellifera (apiMel3, May 2005) - T. castaneum (triCas2, Sep. 2005) Files included in this directory: - chr*.maf.gz files: each contain all the alignments to that particular D. melanogaster chromosome. - The maf/upstream*.maf.gz files contain alignments in regions upstream of annotated transcription starts for FlyBase 5.12 genes with annotated 5' UTRs. These files differ from the standard MAF format: they display alignments that extend from start to end of the upstream region in D. melanogaster, whether or not alignments actually exist. In situations where no alignments exist or the alignments of one or more species are missing, dot (".") is used as a placeholder. Multiple regions of an assembly's sequence may align to a single region in D. melanogaster; therefore, only the species name is displayed in the alignment data and no position information is recorded. The alignment score is always zero in these files. For a description of multiple alignment format (MAF), see http://genome.ucsc.edu/goldenPath/help/maf.html. --------------------------------------------------------------- To download a large file or multiple files from this directory, we recommend that you use ftp rather than downloading the files via our website. To do so: ftp hgdownload.cse.ucsc.edu user name: anonymous password: go to the directory goldenPath/dm3/multiz15way To download multiple files from the UNIX command line, use the "mget" command. mget ... - or - mget -a (to download all the files in the directory) Use the "prompt" command to toggle the interactive mode if you do not want to be prompted for each file that you download. All the files in this directory are freely usable for any purpose. For data use restrictions regarding the individual genome assemblies, see http://genome.ucsc.edu/goldenPath/credits.html.