This directory contains zipped multiple alignments of the human (hg17, May 2004), mouse (mm6, March 2005), and rat (rn3, June 2003) assemblies to the dog (canFam2, May 2005) assembly. The chr*.maf.gz files each contain all the alignments to that particular dog chromosome. For a description of multiple alignment format (MAF), see http://genome.ucsc.edu/goldenPath/help/maf.html. If you plan to download a large file or multiple files from this directory, we recommend that you use ftp rather than downloading the files via our website. To do so, ftp to hgdownload.cse.ucsc.edu, then go to the directory goldenPath/canFam2/multiz4way/. To download multiple files, use the "mget" command: mget ... - or - mget -a (to download all the files in the directory) All the tables in this directory are freely usable for any purpose. The dog genome sequence is made freely available by the Dog Genome Sequencing Project. Please cite the following publication when using these data: Lindblad-Toh K, et al. Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature. 2005 Dec 8;438:803-19.