This directory contains the August 2006 assembly of the cow genome (bosTau3, Baylor Release 3.1), as well as repeat annotations and GenBank sequences. This assembly was produced by the Baylor College of Medicine Human Genome Sequencing Center. For more information on the cow genome, see the project website: http://www.hgsc.bcm.tmc.edu/. Files included in this directory: bosTau3.2bit - contains the complete cow/bosTau3 genome sequence in the 2bit file format. Repeats from RepeatMasker and Tandem Repeats Finder (with period of 12 or less) are shown in lower case; non-repeating sequence is shown in upper case. The utility program, twoBitToFa (available from the kent src tree), can be used to extract .fa file(s) from this file. A pre-compiled version of the command line tool can be found at: http://hgdownload.cse.ucsc.edu/admin/exe/linux.x86_64/ See also: http://genome.ucsc.edu/admin/git.html http://genome.ucsc.edu/admin/jk-install.html bosTau3.agp.gz - Description of how the assembly was generated from fragments. bosTau3.fa.gz - "Soft-masked" assembly sequence in one file. Repeats from RepeatMasker and Tandem Repeats Finder (with period of 12 or less) are shown in lower case; non-repeating sequence is shown in upper case. bosTau3.fa.masked.gz - "Hard-masked" assembly sequence in one file. Repeats are masked by capital Ns; non-repeating sequence is shown in upper case. bosTau3.fa.out.gz - RepeatMasker .out file. RepeatMasker was run with the -s (sensitive) setting. RepeatMasker version: October 6 2006 (open-3-1-6) RepBase Update / RepeatMasker library version: 20061006 bosTau3.trf.bed.gz - Tandem Repeats Finder locations, filtered to keep repeats with period less than or equal to 12, and translated into UCSC's BED format. md5sum.txt - checksums of files in this directory bosTau3.chrom.sizes - Two-column tab-separated text file containing assembly sequence names and sizes. ------------------------------------------------------------------ If you plan to download a large file or multiple files from this directory, we recommend that you use ftp rather than downloading the files via our website. To do so, ftp to hgdownload.cse.ucsc.edu, then go to the directory goldenPath/bosTau3/bigZips. To download multiple files, use the "mget" command: mget ... - or - mget -a (to download all the files in the directory) For conditions of use regarding the Cow genome sequence data, see http://www.hgsc.bcm.tmc.edu/projects/conditions_for_use.html .