Gene interactions and pathways from curated databases and text-mining
SMAD2: top 25 interacting genes (chr18:45335327-45457030)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only SMAD2-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
Gene:               Hide non-SMAD2 interactions     Show top Genes on graph    

Less-frequently mentioned interactions with SMAD2, not among the Top 25
Other genes interacting with SMAD2. Mouse-over to show number of abstracts or databases. Sorted alphabetically (sort by article count).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

ABL1 ABT1 ABTB1 ACR ACTA2 ACTL6A ACTL7A
ACVR1B ACVR1C ACVR2A ADCY2 AGTR1 AHR AHSA1
AIF1L AJUBA AKAP8L AKT1 AKT1S1 AKT2 AKT3
ALX1 ALX4 AMH ANG ANGPT2 ANK3 ANKRD1
ANP32B ANP32E ANTXR2 ANXA1 AP1B1 APBA1 APCS
AQP2 ARFGAP3 ARHGEF1 ARHGEF6 ARHGEF7 ARID1A ARID5A
ARL4D ARNTL ARNTL2 ASCL3 ASF1A ASF1B ASIP
ASPN ATAD3B ATF3 ATF4 ATF5 ATF7IP ATP1A1
ATP1B1 ATP5I ATP5O ATP6V0D1 ATP6V1D ATXN2L AXIN1
BAMBI BARX2 BAZ1A BAZ1B BAZ2A BCL6 BECN1
BEX1 BHMT BIRC2 BIRC3 BIRC8 BMPR2 BPTF
BRCA1 BRCA2 BSND BSX BTBD2 BUB3 C1orf116
C22orf46 CA2 CAB39 CAD CAMK2A CAMK2G CANX
CAV1 CBFA2T2 CBFA2T3 CBX1 CBX3 CBX8 CCDC113
CCDC25 CCNC CCNT1 CCNT2 CCT6A CD19 CDC20
CDC40 CDCA8 CDH1 CDK11A CDK2 CDK4 CDK6
CDKN1A CDKN2B CEP290 CFC1 CFTR CHAF1B CHD4
CHD8 CHGB CITED1 CITED2 CLOCK CLTA CNST
COL1A2 COL2A1 COL6A1 COL6A2 COPS5 CORO1A CPLX1
CPS1 CPSF7 CRB2 CRB3 CREG1 CRK CRX
CSF1 CSH1 CSNK1D CTBP1 CTNNB1 CUL1 CUL5
CXADR CYP11A1 DCAF6 DCAF7 DCP1A DCTN1 DCUN1D1
DDOST DDX1 DDX3Y DGKA DHX8 DKFZp686M216 DLX4
DLX5 DMBX1 DNAJA2 DNAJB5 DNAJC7 DOCK8 DOCK9
DPP10 DPP3 DPP4 DPP6 DPP7 DPP8 DPP9
DRAP1 DVL1 DYNC1H1 DYNC1I1 DYNLRB1 DYRK1A DZIP1
E2F1 E2F2 E2F3 E2F4 E2F5 E2F6 E2F8
ECM1 ECM2 EEF1A1 EGF EIF3D EIF3L EIF4A2
EIF4EBP1 EIF5B ELAC2 EMD ENG EP300 EPAS1
EPB41 EPB41L5 EPHB6 EPS8L1 ERC1 ERCC3 ERCC8
ERLIN1 ESF1 ESR1 ESR2 ETV4 EYA3 F2R
FADD FAM161B FAM83G FBN1 FBN2 FBN3 FBXO3
FGF1 FGF2 FGF8 FHL1 FHL2 FHL3 FIGLA
FLNA FNTB FOXE3 FOXF1 FOXF2 FOXG1 FOXH1
FOXO1 FOXO3 FOXO4 FOXP3 FSHB FST GATA2
GATA4 GATA6 GATAD2B GCH1 GCM1 GDF1 GDF10
GDF11 GDF15 GDF2 GDF3 GDF5 GDF6 GDF7
GDF9 GDI1 GFAP GFER GFI1B GFM2 GLI3
GLUL GNAO1 GNAS GNAT3 GNB2 GOPC GPC1
GRIP1 GRIPAP1 GSC GSK3B GTF2I GTF2IRD1 HAND2
HCLS1 HDAC1 HDAC2 HDAC5 HDAC6 HECTD3 HGF
HIST1H3A HIST1H4A HMGA1 HMGA2 HMGN3 HMOX1 HNF4A
HNRNPA3 HOXA10 HOXA13 HOXA9 HOXB13 HOXC8 HOXD12
HOXD13 HSF1 HSPA1A HSPA4 HSPA8 HSPD1 HTT
HUWE1 ID1 IFNG IFT57 IGF1 IGF2 IGFBP3
IL11 IL16 IL1RAP IL2 IL6 IL8 ILK
INCENP ING2 INHBA INHBB INS INSR IQGAP1
IRAK2 IRF3 IRF7 IRS1 ITGB4 JUN KAT2A
KAT2B KAT5 KDM6B KHDRBS1 KIAA1033 KIAA1109 KIF24
KIF5B KLF10 KLF5 KPNB1 KRIT1 LAMA5 LBX1
LCK LDB1 LEMD3 LHX1 LHX9 LIF LITAF
LMO2 LMO4 LOC101927302 LOX LOXL4 LRCH1 LRPAP1
LTBP1 LTBP2 LYL1 MAFB MAGED1 MALT1 MAP2K1
MAP3K7 MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK15
MAPK4 MAPK6 MAPK7 MAPK8 MAPK9 MAX MBD2
MBD3 MCF2L MED23 MED24 MED27 MED6 MEF2A
MEF2B MEF2C MEF2D MEN1 MFN2 MGA MINA
MKS1 MLLT4 MLXIPL MMP1 MMP2 MMP9 MPP5
MSTN MSX1 MSX2 MTA2 MTCH1 MTMR4 MYC
MYD88 MYL12A MYLIP MYO18A MYO5A MYO5B MYO6
MYOCD MYOD1 MYOG N6AMT1 NAA16 NAGK NANOG
NAP1L1 NCOA6 NCOR2 NEDD4 NEDD9 NEFM NF1
NFATC2 NFKB1 NFKBIA NFYC NGFRAP1 NHLH2 NKX2-1
NKX2-5 NOS1 NOS2 NOS3 NOTCH3 NOTCH4 NOX4
NPAS4 NPHS1 NPHS2 NPPA NPPB NPY4R NR0B2
NR2E3 NTRK1 NUAK2 NUFIP1 NUP153 NUP214 OLIG1
ONECUT3 OPA1 OPN1LW OS9 OTUB1 PABPC1 PAK1
PANX1 PAPOLA PAPPA PARD3 PARD3B PARD6A PARD6B
PARP1 PAX2 PAXBP1 PAXIP1 PBDC1 PBRM1 PBX1
PBX2 PCID2 PDLIM1 PDLIM7 PEX11A PEX19 PEX3
PI3 PI4K2A PIAS3 PIAS4 PIK3CA PIK3R1 PIN1
PITX2 PJA1 PLCB3 PLEKHA2 PLEKHB1 PLG PLIN3
PLN PMF1 POLR3D POU2AF1 POU2F3 POU3F1 POU3F2
POU5F1 PPAN PPARA PPARG PPM1E PPP1CC PPP1R9B
PPP2R1A PPP2R2B PPP2R2D PRDM14 PRDM16 PRELID1 PREX2
PRKAB1 PRKCDBP PRKCI PRKCZ PRKDC PROP1 PRPS2
PRPSAP1 PRPSAP2 PSAP PSG9 PSMD11 PSMD8 PSPC1
PTF1A PTGS2 PTMS PTPN11 PTPN6 PTRF PUS1
PVALB PXMP2 RAB11FIP5 RAB34 RAB38 RAB3A RAB5A
RAN RANBP3 RANBP6 RANBP9 RARB RARG RASD2
RASL12 RBBP4 RBBP7 RBL1 RBL2 RBP4 RBX1
RCOR2 REL RELA RGCC RGP1 RGS4 RGS6
RHEBL1 RHO RHOA RHOBTB1 RHOD RHOJ RILP
RIMS1 RIN1 RIPK1 RIT1 RNF111 RNF123 RNF19A
RNPC3 ROCK1 ROCK2 RPL3 RPL30 RPL4 RPL9
RPS14 RPS2 RPS27A RPS3A RSF1 RUNX1 RUNX1T1
RUNX2 RUVBL1 RXRA RYR2 S100A1 S100A4 SALL4
SAP18 SAP30 SAR1A SCAP SCX SEMA6A SENP2
SERPINE1 SET SF3B2 SFTPC SH2D2A SHH SIK3
SIN3A SIN3B SKI SKIL SKOR2 SKP1 SLC22A6
SLC25A12 SLC25A3 SLC25A5 SLC25A6 SLC27A5 SLC51B SLC9A3R2
SMAD5 SMAD6 SMARCA2 SMARCA5 SMARCD1 SMARCE1 SMN1
SMURF1 SMURF2 SNAI2 SNAI3 SNAPIN SNIP1 SNRNP200
SNRNP70 SNTA1 SNW1 SNX4 SOD1 SORBS1 SOX17
SOX2 SP1 SPARC SPG20 SPP1 SPP2 SPTBN1
SPTBN5 SQRDL SQSTM1 SRA1 SRI SRSF11 SRSF5
SSBP2 SSBP3 SSBP4 SSRP1 SSX2IP ST13 ST5
STAG1 STAMBP STAMBPL1 STAP1 STAT3 STRAP STUB1
STX1A STXBP1 SUB1 SUCLG1 SUCLG2 SUPT16H SUPT6H
SURF6 SYK SYP SYT1 TAF3 TAL1 TAS2R13
TBC1D1 TBX5 TCEAL6 TCP1 TDGF1 TDP1 TEAD2
TEAD4 TERF1 TFAP2D TFCP2 TFDP1 TFDP2 TFDP3
TFEB TGFBR2 TGFBR3 TGFBRAP1 TGIF1 TGM2 TIMP3
TLE6 TMEM102 TNF TNNT1 TNRC6B TOB1 TOB2
TOMM40L TOP1 TP53 TP63 TP73 TPR TPT1
TRADD TRAF6 TRIAP1 TRIM35 TRIM62 TRIP6 TRMT112
TRPC1 TRPC4 TRRAP TSC2 TSPYL2 TTR TUBA1A
TUBA1B TUBA3C TUBA3E TUBA4A TUBAL3 TUBB TUBB1
TUBB2A TUBB2B TUBB4B TUBE1 TUBG2 U2AF2 UBA52
UBB UBC UBE2D2 UBQLN1 UBR5 UCHL5 UHMK1
UNKL USP15 USP28 USP7 USP9X UVRAG VAV2
VCL VCP VEGFA VPS72 WIPI2 WNK1 WNT1
WNT11 WNT16 WNT2 WNT3 WNT4 WNT6 WRNIP1
WWTR1 XIAP XRCC5 XRCC6 YAF2 YEATS4 YTHDF2
YWHAB YWHAQ YWHAZ YY1 ZBTB17 ZEB2 ZFHX3
ZFP42 ZFR ZFYVE9 ZMYND11 ZNF106 ZNF41 ZNF703
ZNF8 ZNHIT6 ZSCAN10
Data information
Please see the Gene Interactions Track Manual.