Gene interactions and pathways from curated databases and text-mining
PIK3CA: top 25 interacting genes (chr3:178866144-178957881)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only PIK3CA-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
Gene:               Hide non-PIK3CA interactions     Show top Genes on graph    

Less-frequently mentioned interactions with PIK3CA, not among the Top 25
Other genes interacting with PIK3CA. Mouse-over to show number of abstracts or databases. Sorted alphabetically (sort by article count).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

ABCB1 ABI1 ABL1 ACD ACTA2 ACTBL2 ACTG2
ADAM12 ADAP1 ADAR ADORA1 ADORA3 ADRBK1 AGTR2
AHSA1 AIFM1 AKT1S1 ALDOA ALYREF AMBP AMPH
ANG ANGPT1 ANGPT2 ANXA2 ANXA6 AP1M2 APLP2
APPL1 AQP3 AR ARAF ARHGEF1 ARHGEF7 ARSK
ATP1A1 ATP1A3 ATP5B ATP5O ATPIF1 ATR ATXN2L
B2M BAD BASP1 BAX BCAR1 BCL10 BCL2
BCL3 BCL5 BCL6 BCL9 BCR BDNF BIRC2
BMP1 BMP10 BMP15 BMP2 BMP3 BMP4 BMP5
BMP6 BMP7 BPNT1 BRAF BRCA1 BSG BTK
C14orf166 C1orf228 CA2 CALM1 CALM2 CALM3 CALR
CANX CASP1 CASP10 CASP12 CASP14 CASP16 CASP2
CASP3 CASP4 CASP5 CASP6 CASP7 CASP8 CASP9
CAT CAV1 CAV2 CAV3 CBFA2T2 CBL CBLB
CBLC CCAR2 CCDC88A CCK CCL2 CCND1 CCND2
CCNG1 CCT5 CD14 CD19 CD2 CD247 CD28
CD38 CD3Z CD4 CD79A CD79B CD80 CD86
CDC123 CDC16 CDC20 CDC23 CDC26 CDC27 CDC34
CDC37 CDC40 CDC42 CDC45 CDC6 CDC7 CDC73
CDH1 CDH5 CDK5 CDKN1A CEBPA CEBPB CHKA
CHUK CKB CNTRL CORO2A CPOX CPSF1 CREB1
CREB3 CREB5 CRK CRKL CSE CSF1 CSF1R
CSF2 CSF2RA CSF2RB CTGF CTLA4 CTNNA1 CTNNB1
CUX1 CX3CL1 CXCL10 CXCL11 CXCL12 CXCL9 CXCR4
CYP19A1 DAB1 DAB2IP DDIT3 DDX17 DDX3X DDX3Y
DDX5 DGKZ DHX15 DHX30 DHX9 DLG1 DNAJA1
DNAJB11 DNAJB6 DNM1L E2F1 ECM1 ECM2 EDG1
EEF1A1 EEF1A1P5 EEF1A2 EEF2 EFNA1 EFNB2 EGF
EGFR EGR1 EHMT1 EIF2AK1 EIF4EBP1 EIF5A EIF5A2
EIF5AL1 ELAVL1 ENO1 ENY2 EPB41L1 EPHB1 EPHB4
EPO EPS8 ERBB2 ERBB4 ERH ESR1 ESR2
F11R F2RL1 FAS FASLG FBL FCER1A FCER1G
FCGR1A FCGR3A FCGR3B FES FGA FGB FGF1
FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17
FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23
FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9
FGFR1OP FGFR1OP2 FGFR2 FGG FGR FIGF FLNB
FLT1 FLT3 FOS FOSL1 FOXO1 FOXO3 FOXO4
FOXO6 FOXP3 FRS2 FTL FUS FYN GAB1
GAB2 GABRB1 GAPDH GDF15 GDNF GFRA1 GH1
GHR GJA1 GNA11 GNA14 GNA15 GNAI1 GNAI2
GNAI3 GNAO1 GNAQ GNB1 GNB2 GNB3 GNB4
GNB5 GNE GNG10 GNG11 GNG12 GNG13 GNG2
GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2
GPER1 GPR1 GPR101 GPR107 GPR108 GPR110 GPR111
GPR112 GPR113 GPR114 GPR115 GPR116 GPR119 GPR12
GPR123 GPR124 GPR125 GPR126 GPR128 GPR132 GPR133
GPR135 GPR137 GPR139 GPR141 GPR142 GPR143 GPR144
GPR146 GPR148 GPR149 GPR15 GPR150 GPR151 GPR152
GPR153 GPR155 GPR156 GPR157 GPR158 GPR160 GPR161
GPR162 GPR17 GPR171 GPR173 GPR174 GPR176 GPR179
GPR18 GPR180 GPR182 GPR183 GPR19 GPR20 GPR21
GPR22 GPR25 GPR26 GPR27 GPR3 GPR31 GPR32
GPR33 GPR34 GPR35 GPR36 GPR37 GPR39 GPR4
GPR42 GPR45 GPR50 GPR52 GPR55 GPR56 GPR6
GPR61 GPR62 GPR63 GPR64 GPR65 GPR68 GPR75
GPR78 GPR79 GPR82 GPR83 GPR84 GPR85 GPR87
GPR88 GPR97 GPR98 GPS2 GRAP2 GRB2 GRIN2B
GRP GSK3A GSK3B GSN GTPBP1 GYS1 GYS2
H2AFJ H2BFS HBEGF HCST HDAC1 HDAC2 HDAC3
HGF HIF1A HIST1H1A HIST1H1T HIST1H2AB HIST1H2AC HIST1H2AD
HIST1H2AE HIST1H2AG HIST1H2AH HIST1H2AJ HIST1H2BB HIST1H2BD HIST1H2BH
HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A
HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H2BF HIST3H2A HIST3H2BB
HLA-A HLA-B HLA-DRA HLA-DRB1 HLA-E HMGB1 HMOX1
HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPAB HNRNPC HNRNPD
HNRNPDL HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL
HNRNPR HNRNPU HNRNPUL1 HRAS HRG HRNR HSP90AA1
HSP90AB1 HSPB1 HSPG2 ICAM1 ICOS IFI27 IFNB1
IFNG IFNGR1 IGF1R IGF2 IGF2BP1 IGF2BP2 IGF2BP3
IGFBP3 IGHE IGHG1 IGHG2 IGHG3 IGHG4 IGKC
IGKV1-5 IGKV4-1 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7
IKBKB IKBKG IL10 IL11 IL12A IL12B IL12RB1
IL13 IL15 IL16 IL17A IL18 IL19 IL1A
IL1B IL1R1 IL1RAP IL1RN IL2 IL20 IL21
IL22 IL23A IL23R IL24 IL25 IL26 IL27
IL2RB IL2RG IL3 IL31 IL32 IL33 IL34
IL37 IL3RA IL4 IL4R IL5 IL5RA IL6
IL6ST IL7 IL8 IL9 ILF2 ILF3 ILK
INPP5B INPP5E INS-IGF2 INSR INSRR IRF1 IRF6
IRS1 IRS2 IRS4 ITGA5 ITGA6 ITGAV ITGB1
ITGB2 ITGB3 ITGB4 ITIH1 ITIH4 ITK Il7r
JAK1 JAK2 JAK3 JUN JUP KHDRBS1 KIRREL
KIT KITLG KL KLB KLRC2 KLRD1 KLRK1
KRAS LAT LAT2 LCK LDHB LDLR LEP
LGALS3 LGALS3BP LIF LPA LRPPRC LTB LYN
MAP2K1 MAP2K2 MAP3K5 MAP3K7 MARCKS MASP1 MATR3
MCL1 MDH2 MDM2 MET MIF MLST8 MMP1
MMP10 MMP11 MMP12 MMP13 MMP14 MMP15 MMP16
MMP17 MMP19 MMP2 MMP20 MMP21 MMP24 MMP25
MMP26 MMP27 MMP28 MMP3 MMP7 MMP8 MMP9
MOK MOV10 MRAS MRE11A MRPL12 MRPS14 MRPS17
MRPS18B MRPS22 MRPS23 MRPS25 MRPS26 MRPS27 MRPS28
MRPS34 MS4A2 MSC MT3 MUC1 MUC8 MYC
MYCN MYD88 MYH10 MYH14 MYH9 MYL6 MYLIP
MYO1C MYOG NA NANOG NBPF8 NCF1 NCF4
NCOR1 NEDD9 NEFH NFAT5 NFE2L2 NFKBIA NGF
NGFB NKRF NM NOS1 NOS2 NOS3 NOTCH1
NOX1 NOX3 NOX4 NOX5 NPHS1 NPHS2 NPM1
NPY4R NR3C1 NRAS NRG1 NTF3 NTRK1 NTRK2
NTRK3 OCRL ODC1 PABPC1 PABPC4 PABPN1 PAICS
PAK1 PAK2 PAK3 PAK4 PAK6 PAK7 PARP1
PBK PCBP1 PCBP2 PCBP3 PCID2 PCNA PDE3B
PDE4D PDGFB PDGFRA PDGFRB PDK1 PDLIM7 PDPK1
PDX1 PGAM1 PGAM2 PGAM4 PGF PGK1 PGP
PGR PHKA2 PHLDA1 PI3 PIK3AP1 PIK3C2A PIK3C2B
PIK3C2G PIK3CB PIK3CD PIK3CG PIK3IP1 PIK3R1 PIK3R2
PIK3R3 PIK3R4 PIK3R5 PIK3R6 PIP PIP4K2A PIP4K2C
PIP5K1A PIP5K1B PIP5K1C PKD1 PKD2 PKD3 PLA2G1B
PLA2G4A PLAT PLAU PLCB1 PLCB2 PLCB3 PLCB4
PLCD1 PLCD3 PLCD4 PLCE1 PLCG1 PLCG2 PLCZ1
PLD1 PLD2 PLD3 PLD4 PLD5 PLD6 PLEK
PON2 POT1 POTEKP PPARG PPIA PPP1CA PPP1CB
PPP1CC PPP1R3A PRDX2 PRDX6 PREX1 PRKAA1 PRKAA2
PRKAB1 PRKAB2 PRKACB PRKACG PRKAG1 PRKAG2 PRKAR1A
PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCI PRKCZ PRKRA
PRL PSEN1 PTBP1 PTCD3 PTGES PTGS2 PTH
PTK2 PTK6 PTK7 PTMA PTPN1 PTPN11 PTTG1
RAB5A RAC1 RAC2 RAC3 RAD50 RAE1 RAF1
RALY RASD2 RASGRP3 RBBP4 RBBP7 RBL2 RBMX
RHEB RHOA RHOG RICTOR RLN1 RLN2 RLN3
RNF19A RPL17 RPL22 RPL23 RPL28 RPLP0 RPLP0P6
RPLP1 RPS10 RPS11 RPS12 RPS18 RPS2 RPS20
RPS24 RPS3 RPS4X RPS5 RPS6KB1 RPSA RPTOR
RRAS2 RTCB RUNX2 RUVBL1 RUVBL2 S100A10 SEMG1
SEMG2 SERPINE1 SETD2 SGK1 SGK2 SGK3 SH2D2A
SH3KBP1 SHANK3 SHC1 SHC2 SHC3 SIRT1 SKP2
SLC22A3 SLC25A16 SLC25A3 SLC25A31 SLC25A4 SLC25A5 SLC2A1
SLC2A4 SLC9A1 SLC9A3R1 SLPI SMAD1 SMAD2 SMAD3
SMAD4 SMAD5 SMAD6 SMAD7 SMAD9 SMN1 SMO
SNAI2 SNRPD3 SNRPF SOAT1 SOCS3 SOS1 SP1
SPP1 SPTA1 SQSTM1 SRC SREBF1 SSR1 SST
STAT1 STAT3 STAT5B STAT6 STAU1 STK10 STK11
STK16 STK19 STK24 STK25 STK3 STK31 STK33
STK35 STK36 STK38 STK39 STK4 STK40 SYK
SYNCRIP SYNJ1 SYNJ2 SYT1 TAT TBL1X TBL1XR1
TCF12 TCF15 TCF19 TCF20 TCF21 TCF23 TCF24
TCF25 TCF3 TCF4 TCF7 TEK TERF1 TERF2
TERF2IP TFRC TGFB1 TGFB2 TGFB3 TIAM2 TIMM50
TINF2 TLR1 TLR10 TLR2 TLR3 TLR4 TLR5
TLR6 TLR7 TLR8 TLR9 TMED7 TNF TNFSF10
TNFSF13B TP53 TPI1 TPO TRA@ TRAT1 TRB@
TREM2 TRIM21 TRIM24 TRNAE1 TSC2 TUBA1A TUBA1C
TUBA4A TUBB TUBB4B TXK TYR TYROBP UBC
UBTF UCN UFD1L UNC5B UPF1 UVRAG VARS2
VAV1 VAV2 VAV3 VCAM1 VEGF VEGFC VLDLR
WDR5 WDR6 WNK1 WNT1 WNT11 WNT16 WNT2
WNT3 WNT4 WNT6 XIAP XRCC5 XRCC6 XRN2
YBX3 YES1 YWHAE YWHAG YWHAH YWHAQ YWHAZ
ZAP70 ZGLP1 ZMYM2
Data information
Please see the Gene Interactions Track Manual.