Gene interactions and pathways from curated databases and text-mining
IRF6: top 25 interacting genes (chr1:209958961-209979487)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only IRF6-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with IRF6, not among the Top 25
Other genes interacting with IRF6. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

MAPK7 ▸ MAPK6 ▸ IFNG ▸ EPHB2 ▸ NFKBIA ▸ NOS1 ▸ CCL2 ▸
CD14 ▸ ICAM1 ▸ CPOX ▸ IL4 ▸ JUN ▸ IL18 ▸ IL2 ▸
NOS3 ▸ IL5 ▸ IL13 ▸ FOS ▸ PTBP1 ▸ HNRNPH1 ▸ HNRNPF ▸
PTBP2 ▸ IL33 ▸ IL3 ▸ IL15 ▸ IL37 ▸ IL32 ▸ IL19 ▸
IL21 ▸ IL22 ▸ IL11 ▸ IL24 ▸ IL16 ▸ IL7 ▸ IL20 ▸
IL9 ▸ IL31 ▸ IL34 ▸ IL26 ▸ IL27 ▸ IL25 ▸ TLR2 ▸
CSF2 ▸ MMP9 ▸ AKT1 ▸ AKT2 ▸ SYT1 ▸ AHSA1 ▸ AKT3 ▸
CASP3 ▸ CASP1 ▸ CXCL10 ▸ CASP9 ▸ CASP8 ▸ CASP6 ▸ CASP4 ▸
CASP16 ▸ CASP10 ▸ CASP7 ▸ CASP14 ▸ CASP5 ▸ CASP2 ▸ CASP12 ▸
IFNB1 ▸ VCAM1 ▸ IL1RN ▸ RNF19A ▸ GRAP2 ▸ UMOD ▸ WNK1 ▸
LBP ▸ SELE ▸ TLR3 ▸ TLR9 ▸ HMOX1 ▸ TLR1 ▸ CCL3 ▸
VEGFA ▸ TLR7 ▸ ANXA6 ▸ CFP ▸ TLR5 ▸ CRK ▸ TLR6 ▸
LANCL1 ▸ TLR8 ▸ GPI ▸ TLR10 ▸ STAT1 ▸ MMP2 ▸ CD86 ▸
CD79A ▸ CD40 ▸ HMGB1 ▸ MMP1 ▸ MPO ▸ NOX1 ▸ CHUK ▸
ITGAM ▸ IKBKB ▸ POLDIP2 ▸ CD80 ▸ STAT3 ▸ IRF3 ▸ MMP3 ▸
MIP ▸ MYD88 ▸ NOX4 ▸ TP63 ▸ MMP13 ▸ MUC1 ▸ MUC2 ▸
NOX5 ▸ NOX3 ▸ MMP8 ▸ CA2 ▸ TGFB1 ▸ MMP14 ▸ MUC7 ▸
IRAK1 ▸ CXCL1 ▸ MMP11 ▸ MMP12 ▸ MUC16 ▸ MMP25 ▸ MMP20 ▸
MMP19 ▸ MMP28 ▸ MMP26 ▸ MMP10 ▸ MMP24 ▸ RABEPK ▸ CXCL2 ▸
MMP27 ▸ CD46 ▸ MMP21 ▸ MMP16 ▸ MMP17 ▸ MUC4 ▸ MMP15 ▸
MMP7 ▸ MUC20 ▸ TCF7 ▸ TCF4 ▸ TCF25 ▸ MUC15 ▸ TCF23 ▸
MUC13 ▸ MUC21 ▸ TCF20 ▸ MUC17 ▸ CXCL9 ▸ TCF24 ▸ TCF15 ▸
MUC8 ▸ MUC22 ▸ TCF19 ▸ TCF3 ▸ MUC6 ▸ MUC12 ▸ IKBKG ▸
TCF21 ▸ TCF12 ▸ MUC19 ▸ SERPINE1 ▸ HLA-DRA ▸ CXCL11 ▸ LYZ ▸
WDR61 ▸ CTR9 ▸ LEO1 ▸ PAF1 ▸ CXCL12 ▸ CDC73 ▸ PLA2G4A ▸
CXCL13 ▸ PTGS1 ▸ CXCL5 ▸ HLA-DRB1 ▸ LEP ▸ IRF1 ▸ CXCL16 ▸
CSF3 ▸ CXCL6 ▸ SOD1 ▸ C1orf228 ▸ SOD2 ▸ IRAK4 ▸ ITGB2 ▸
MIPEP ▸ SOD3 ▸ CXCL17 ▸ PI3 ▸ IDO1 ▸ IL23A ▸ CXCL3 ▸
PGF ▸ CXCL14 ▸ HDC ▸ PIK3R1 ▸ REL ▸ PIK3CA ▸ CRH ▸
PDCD11 ▸ HGF ▸ SAA1 ▸ IRAK3 ▸ SOCS3 ▸ CSF1 ▸ LTB ▸
EGR1 ▸ MYLIP ▸ CD83 ▸ SLC25A10 ▸ PLA2G1B ▸ ICAM5 ▸ ICAM2 ▸
ICAM3 ▸ NANOS2 ▸ ICAM4 ▸ NM ▸ MUC5AC ▸ INS ▸ IRAK2 ▸
NUP43 ▸ ARG1 ▸ FAS ▸ MIF ▸ CD4 ▸ EDN1 ▸ PTGES ▸
TNPO1 ▸ CEBPB ▸ IGF1 ▸ SOAT1 ▸ TNFSF11 ▸ TBCE ▸ SLPI ▸
BPI ▸ SETD2 ▸ CCR2 ▸ CREB3 ▸ CREB1 ▸ NCF1 ▸ CCL4 ▸
FASLG ▸ HDAC1 ▸ CAT ▸ CREB5 ▸ DEFB4B ▸ DUSP1 ▸ IRF7 ▸
CEBPA ▸ PTX3 ▸ ARF4 ▸ SELP ▸ ARF6 ▸ S100A12 ▸ SRC ▸
MDM2 ▸ HDAC2 ▸ MAP3K8 ▸ IFI44 ▸ ARF1 ▸ ARF3 ▸ MDM1 ▸
CD69 ▸ IRF2 ▸ CCL20 ▸ MDM4 ▸ ARF5 ▸ CRP ▸ CCR7 ▸
PLD1 ▸ PLD6 ▸ TNFRSF11B ▸ IRF8 ▸ PLD5 ▸ PLG ▸ RHOA ▸
PLD4 ▸ HIF1A ▸ GP2 ▸ RAC1 ▸ ARG2 ▸ GP9 ▸ PPARG ▸
NGF ▸ MTOR ▸ RBBP4 ▸ CISH ▸ PLD3 ▸ PLD2 ▸ NFKBIB ▸
IRF4 ▸ APOE ▸ ABCC1 ▸ GP6 ▸ SLC17A5 ▸ GP5 ▸ ALB ▸
CCR5 ▸ AVP ▸ CCL5 ▸ AGTR2 ▸ CDCA5 ▸ CD40LG ▸ NOD2 ▸
BAX ▸ APOB ▸ SERPINB2 ▸ PGD ▸ TRAF6 ▸ PRKCA ▸ CCND1 ▸
ADAM11 ▸ SP1 ▸ ZFP36 ▸ TREM1 ▸ IL17D ▸ GJA1 ▸ MAPKAPK2 ▸
BCL2 ▸ GIT2 ▸ JAK2 ▸ PPARA ▸ HBD ▸ BDNF ▸ APC ▸
AHR ▸ TIMP1 ▸ CORT ▸ HSPG2 ▸ ATP5O ▸ ODC1 ▸ LPL ▸
IRF9 ▸ IL2RA ▸ IFNA4 ▸ PDE4B ▸ LCN2 ▸ FCER2 ▸ LY96 ▸
CXCR4 ▸ CALM3 ▸ CAV1 ▸ IL1R1 ▸ BCL10 ▸ LYN ▸ STS ▸
PLAU ▸ SELL ▸ LITAF ▸ ATF2 ▸ TBK1 ▸ LIF ▸ RBBP7 ▸
EGFR ▸ GNRH1 ▸ IRF5 ▸ LTF ▸ F3 ▸ PTK6 ▸ P2RX7 ▸
NCF2 ▸ BTK ▸ PRL ▸ SLC27A5 ▸ SUDS3 ▸ SPP1 ▸ SAP130 ▸
TNFSF13B ▸ PRDX2 ▸ SIN3A ▸ HSPD1 ▸ CCR3 ▸ TFPI ▸ ARID4B ▸
CSRP1 ▸ CD2 ▸ IL17A ▸ SOCS1 ▸ CCR6 ▸ ADM ▸ MT3 ▸
GDNF ▸ GAL ▸ NA ▸ UCN ▸ PTK2 ▸ SAP30 ▸ RAF1 ▸
AGTR1 ▸ ATP8A2 ▸ MNAT1 ▸ PTK7 ▸ MOCOS ▸ TNFSF10 ▸ IFNA2 ▸
CYP3A ▸ BCL3 ▸ EIF2AK2 ▸ PARP1 ▸ MLYCD ▸ CD276 ▸ CCR8 ▸
IFNA1 ▸ PHKA2 ▸ CEL ▸ IL2RB ▸ RETN ▸ SPHK1 ▸ FGB ▸
IFNA10 ▸ PRG2 ▸ TP53 ▸ GCHFR ▸ IKBKAP ▸ IFNA7 ▸ MAP2K1 ▸
CXCR1 ▸ ACE ▸ MAP3K14 ▸ SETBP1 ▸ NOTCH1 ▸ NLRP3 ▸ IFNA21 ▸
IFNA16 ▸ MSH3 ▸ IFNA8 ▸ PRG4 ▸ CCR9 ▸ STAT5A ▸ IFNA13 ▸
CD44 ▸ CEBPD ▸ ECM2 ▸ IFNA17 ▸ NEDD9 ▸ RELB ▸ PRG3 ▸
LDLR ▸ CRAT ▸ ACP2 ▸ IFNA5 ▸ LIPA ▸ IFNA14 ▸ CCR10 ▸
IFNA6 ▸ MOK ▸ CD8A ▸ CCR4 ▸ ECM1 ▸ ETS2 ▸ APP ▸
TGFB2 ▸ ADAM17 ▸ JAK1 ▸ CSE ▸ CCR1 ▸ SLC22A3 ▸ APCS ▸
ALG1 ▸ NEU1 ▸ TNP1 ▸ CCL24 ▸ C9orf3 ▸ OLR1 ▸ NOTCH3 ▸
MSH4 ▸ TRAM1 ▸ SYK ▸ PLIN2 ▸ HDAC11 ▸ CAV3 ▸ LTA ▸
MSH6 ▸ OCLN ▸ F2RL1 ▸ EDN2 ▸ TNP2 ▸ IGFBP3 ▸ ANXA1 ▸
F2R ▸ NOTCH4 ▸ CXCR2 ▸ SAA4 ▸ FBXO32 ▸ SERPING1 ▸ HDAC3 ▸
GIF ▸ TNFRSF1A ▸ TYK2 ▸ SH3D19 ▸ TGFB3 ▸ EIF4EBP1 ▸ TF ▸
TNFRSF1B ▸ CADM1 ▸ THBD ▸ CRYGEP ▸ TRAM2 ▸ PLAUR ▸ RAC2 ▸
BCL6 ▸ TXN ▸ PTPN11 ▸ UCP2 ▸ MSH5 ▸ SLCO6A1 ▸ MSH2 ▸
NOTCH2 ▸ SAA2 ▸ ABCB1 ▸ EDN3 ▸ S100A8 ▸ SIGLEC7 ▸ BCL9 ▸
WAS ▸ CAMP ▸ BCL5 ▸ MAF ▸ CD55 ▸ ATF3 ▸ PAM ▸
GHR ▸ ABCA1 ▸ NOD1 ▸ CNR2 ▸ PCBD1 ▸ CEBPZ ▸ CNP ▸
COA5 ▸ MTA2 ▸ PTX4 ▸ GIT1 ▸ DDX58 ▸ CCND2 ▸ COA4 ▸
DDIT3 ▸ ITGAX ▸ UPK3B ▸ MAP3K7 ▸ GPX2 ▸ ICOSLG ▸ CIITA ▸
FADD ▸ AQP5 ▸ MT4 ▸ GPX5 ▸ ADCY9 ▸ VIP ▸ SLC2A1 ▸
HMGCR ▸ CTLA4 ▸ SMC6 ▸ MARCKS ▸ PRKAG1 ▸ TYR ▸ PLTP ▸
NEU3 ▸ PPARGC1A ▸ S12 ▸ GPX1 ▸ RPTOR ▸ SIGIRR ▸ JUNB ▸
SMC3 ▸ COA3 ▸ MET ▸ ALPI ▸ GPX4 ▸ CDC42 ▸ GSK3B ▸
OXTR ▸ MRXS5 ▸ GATA2 ▸ PGC ▸ NEU4 ▸ SMC5 ▸ CETP ▸
PLAT ▸ CCL18 ▸ S7 ▸ ANXA5 ▸ SMC4 ▸ NPY4R ▸ HP ▸
STX1A ▸ EPB42 ▸ SMC2 ▸ FPR1 ▸ CYBB ▸ VIPR1 ▸ GPX8 ▸
JAK3 ▸ PGP ▸ HDAC6 ▸ CD38 ▸ PRKAG2 ▸ POU2F2 ▸ UBL3 ▸
SEC14L2 ▸ SCARB1 ▸ PLCG1 ▸ PRKAB1 ▸ TSPO ▸ CYP2B6 ▸ CTRL ▸
WNT2 ▸ ELAVL1 ▸ CHD4 ▸ TOLLIP ▸ PRKAB2 ▸ CD28 ▸ NAALADL1 ▸
FGFR3 ▸ IFIT2 ▸ NEU2 ▸ CAV2 ▸ LPO ▸ GFAP ▸ A2M ▸
POMC ▸ ISG15 ▸ GPX6 ▸ PRKAA2 ▸ CD8B ▸ TFRC ▸ ACO1 ▸
GAST ▸ GPX3 ▸ PRDX1 ▸ TRAF1 ▸ FXR1 ▸ CES1 ▸ ARC ▸
TECR ▸ CX3CL1 ▸ COA1 ▸ CD1A ▸ FXR2 ▸ LOX ▸ S11 ▸
COA6 ▸ SLC7A2 ▸ AGXT ▸ GPX7 ▸ CD19 ▸ EIF4E ▸ NPPA ▸
CDH13 ▸ CTSB ▸ ACHE ▸ GATA3 ▸ PRKAA1 ▸ BIRC3 ▸ JUND ▸
CES2 ▸ PECAM1 ▸ ADCY6 ▸ LTC4S ▸ TPGS1 ▸ CYP1A1 ▸ NPR1 ▸
SMN1 ▸ VWF ▸ AKT1S1 ▸ CTSL ▸ TPX2 ▸ FPR2 ▸ KLF4 ▸
CAPN3 ▸ PLEK ▸ PTHLH ▸ MARCO ▸ EDNRA ▸ TPO ▸ AQP4 ▸
PARP8 ▸ PKD1 ▸ PARP14 ▸ CAPN10 ▸ PLCG2 ▸ PVR ▸ CPP ▸
SDC2 ▸ SST ▸ CAPN13 ▸ IFN1@ ▸ ITGB1 ▸ CX3CR1 ▸ QRICH1 ▸
CES3 ▸ ESAM ▸ IL13RA1 ▸ GATA1 ▸ CCL4L2 ▸ MCM4 ▸ RPS6KB1 ▸
CADM3 ▸ MST1R ▸ MTDH ▸ ITGAL ▸ HPGDS ▸ CAPN11 ▸ DST ▸
IL2RG ▸ HAMP ▸ ISG20 ▸ AMBP ▸ CD9 ▸ HDAC8 ▸ MCOLN1 ▸
MCM6 ▸ GPS2 ▸ CAPN7 ▸ GATA6 ▸ IL1RAP ▸ SDC4 ▸ AQP1 ▸
HCLS1 ▸ TIMP3 ▸ AQP8 ▸ PARP15 ▸ HDAC10 ▸ TBL1XR1 ▸ S1PR3 ▸
EPB41 ▸ C5AR1 ▸ CYP4F22 ▸ RNPEP ▸ CYP4F3 ▸ CADM4 ▸ TPGS2 ▸
TXNRD2 ▸ MCM7 ▸ PRKAR2A ▸ EPS8 ▸ PPP2R2B ▸ LRP1 ▸ GATA4 ▸
PARP6 ▸ ADCY1 ▸ IL6R ▸ PPP2CA ▸ RASIP1 ▸ TBL1X ▸ CYP4F12 ▸
SLC5A1 ▸ EPS15 ▸ FGF2 ▸ WNT5A ▸ P2RX4 ▸ C4BPA ▸ PDCD2 ▸
MT-CYB ▸ NDUFAB1 ▸ CTNNB1 ▸ CD1D ▸ PRKACB ▸ TAT ▸ FGF9 ▸
GSR ▸ CYP4F11 ▸ PPP2R1A ▸ CLU ▸ CYP4F2 ▸ CCL1 ▸ NPY ▸
CAPN5 ▸ S100A9 ▸ PARP3 ▸ CYP1A2 ▸ NTRK1 ▸ LAMP2 ▸ PRX ▸
FOXP3 ▸ ADCY7 ▸ KLK3 ▸ CLDN1 ▸ ADCY5 ▸ ADCY2 ▸ CNR1 ▸
SMAD7 ▸ FMR1 ▸ SERPINB6 ▸ SREBF1 ▸ SP100 ▸ CAPN6 ▸ CAPN8 ▸
KCNMA1 ▸ BCAP31 ▸ CD5 ▸ AGT ▸ MCM2 ▸ GLA ▸ CPZ ▸
NTF3 ▸ PMPCB ▸ INSR ▸ LAMP1 ▸ MAP2K3 ▸ PPARD ▸ LGALS3 ▸
PRKAR2B ▸ PDGFA ▸ C1QB ▸ PDGFB ▸ HDAC5 ▸ IGH ▸ HDAC9 ▸
MCM5 ▸ CAPN1 ▸ G6PD ▸ ADCY3 ▸ CAPN15 ▸ MICE ▸ SLC9A1 ▸
SMAD4 ▸ LAMP5 ▸ ACAN ▸ MCM3 ▸ PARP12 ▸ PARP16 ▸ IRG1 ▸
F12 ▸ PIR ▸ APOA1 ▸ S1PR1 ▸ SLC11A2 ▸ TUBGCP2 ▸ PRDX5 ▸
RSAD2 ▸ IDS ▸ ERF ▸ SIRT1 ▸ ERP27 ▸ NCOR1 ▸ ADAMTS5 ▸
PRKCB ▸ TNFSF13 ▸ CAPN14 ▸ IL1R2 ▸ CAPN2 ▸ LAMP3 ▸ PLN ▸
GATA5 ▸ ELANE ▸ BDKRB1 ▸ PARP11 ▸ VDR ▸ MAP2K6 ▸ CAPN9 ▸
PGR ▸ TFAP2A ▸ PARP4 ▸ KCNH4 ▸ PARP10 ▸ HDAC7 ▸ RIPK2 ▸
ABL1 ▸ PRKAR1A ▸ CD58 ▸ PKD2 ▸ MTA1 ▸ USP7 ▸ TRIM63 ▸
C1QA ▸ MCS ▸ NR1I2 ▸ PTEN ▸ KHSRP ▸ MEPE ▸ ADCY4 ▸
ADCY8 ▸ PRKAR1B ▸ REG3A ▸ MBD3 ▸ BCR ▸ KITLG ▸ ADCY10 ▸
NR4A1 ▸ NFKBIZ ▸ MAP2K2 ▸ NCF4 ▸ MLST8 ▸ CORO2A ▸ PDCD1LG2 ▸
NANOS1 ▸ ERP44 ▸ PRDM1 ▸ SPHK2 ▸ ASS1 ▸ NQO1 ▸ PKD3 ▸
SPAG8 ▸ PLA2G7 ▸ USP14 ▸ LGALS1 ▸ RHO ▸ ETS1 ▸ ERP29 ▸
HSP90AA1 ▸ CAPN12 ▸ HDAC4 ▸ MUC5B ▸ STAR ▸ FGF21 ▸ FEV ▸
OSM ▸ CADM2 ▸ IKBKE ▸ IL18BP ▸ QRICH2 ▸ PARP2 ▸ DOK3 ▸
RHOB ▸ CROT ▸ FOSL1 ▸ AQP2 ▸ PARP9 ▸ PRTN3 ▸ FCGR1A ▸
MAL ▸ CYP4F8 ▸ PRKACG ▸ ACSL1 ▸ FST ▸ GALT ▸ MID1 ▸
COPS4 ▸ PCAF ▸ RFX3 ▸ ZBTB3 ▸ CREBBP ▸ COPS2 ▸ COPS5 ▸
ARHGAP29 ▸ GTF2A1 ▸ TAF1 ▸ SMARCD1 ▸ TLX2 ▸ GPS1 ▸ BNC2 ▸
GTF2E1 ▸ NR3C1 ▸ UBC ▸ CDK4 ▸ ONECUT1 ▸ GTF3A ▸ COPS6 ▸
Data information
Please see the Gene Interactions Track Manual.