Gene interactions and pathways from curated databases and text-mining
IL8: top 25 interacting genes
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only IL8-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with IL8, not among the Top 25
Other genes interacting with IL8. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

TLR4 ▸ TLR2 ▸ FOS ▸ IL4 ▸ IL2 ▸ CSF2 ▸ IL17A ▸
ICAM1 ▸ TLR3 ▸ NM ▸ TLR5 ▸ CD40 ▸ PTGS2 ▸ IL13 ▸
VEGFA ▸ AHSA1 ▸ TLR9 ▸ TLR1 ▸ CA2 ▸ CCL2 ▸ TLR8 ▸
IL3 ▸ TLR7 ▸ IL15 ▸ TLR6 ▸ RNF19A ▸ LTA ▸ TGFB1 ▸
IL5 ▸ TLR10 ▸ IL33 ▸ TCF21 ▸ TCF4 ▸ IL18 ▸ NOS2 ▸
F2RL1 ▸ IL22 ▸ TCF3 ▸ TCF19 ▸ TCF15 ▸ TCF23 ▸ TCF20 ▸
TCF12 ▸ TCF24 ▸ TCF25 ▸ TCF7 ▸ CRK ▸ CSE ▸ PIK3R1 ▸
NA ▸ PIK3CA ▸ NFKBIA ▸ IL32 ▸ LPA ▸ IL1RN ▸ MMP9 ▸
PAF1 ▸ EGF ▸ CTR9 ▸ WDR61 ▸ GRAP2 ▸ CDC73 ▸ LEO1 ▸
APOB ▸ IL31 ▸ HGF ▸ MMP2 ▸ IFNB1 ▸ IL11 ▸ CXCR1 ▸
IL7 ▸ S100A8 ▸ IL20 ▸ ITGAM ▸ FGF2 ▸ IL19 ▸ IL9 ▸
IL21 ▸ IL16 ▸ IL25 ▸ POLDIP2 ▸ IL26 ▸ IL24 ▸ IL37 ▸
MMP3 ▸ SAA1 ▸ IL27 ▸ FAS ▸ IL34 ▸ INS ▸ NOS1 ▸
MIF ▸ EGFR ▸ AKT2 ▸ PI3 ▸ CRP ▸ AKT3 ▸ CXCR2 ▸
AKT1 ▸ ALB ▸ CD14 ▸ IKBKB ▸ CALM3 ▸ MMP1 ▸ CASP4 ▸
MMP13 ▸ CASP3 ▸ NOX1 ▸ CASP10 ▸ CASP5 ▸ NOS3 ▸ CASP8 ▸
CASP14 ▸ CASP1 ▸ CASP7 ▸ CASP6 ▸ CASP2 ▸ F2R ▸ CD40LG ▸
NOX4 ▸ CASP16 ▸ CASP9 ▸ CASP12 ▸ HMGB1 ▸ NOX3 ▸ PLG ▸
PTX3 ▸ NOX5 ▸ NOD1 ▸ SELE ▸ ITGB2 ▸ LIF ▸ TNFSF10 ▸
CHUK ▸ MYLIP ▸ IGF1 ▸ PTK7 ▸ TGFB2 ▸ PTK6 ▸ MYD88 ▸
PTK2 ▸ PRG3 ▸ TREM1 ▸ MMP8 ▸ PRG4 ▸ IL12B ▸ GP5 ▸
GP6 ▸ GP9 ▸ CXCL12 ▸ LEP ▸ GP2 ▸ PTX4 ▸ MUC1 ▸
ERVK-6 ▸ SRC ▸ STAT3 ▸ IFNA2 ▸ MAP3K7 ▸ PRG2 ▸ IKBKG ▸
PRKAR1B ▸ VCAM1 ▸ IFNA14 ▸ PRKAR2B ▸ MPO ▸ IFNA13 ▸ SOD2 ▸
IFNA1 ▸ SOD1 ▸ VIP ▸ PRKAR1A ▸ HNRNPH1 ▸ IFNA4 ▸ SERPINE1 ▸
PTBP1 ▸ CRH ▸ HDAC2 ▸ IFNA6 ▸ MMP7 ▸ WNK1 ▸ PAM ▸
IL12A ▸ IFNA17 ▸ S100A12 ▸ PRKAR2A ▸ PRKACB ▸ MMP14 ▸ PTBP2 ▸
IFNA8 ▸ IFNA7 ▸ IFNA5 ▸ SOD3 ▸ IFNA21 ▸ PRKACG ▸ IFNA10 ▸
HNRNPF ▸ PLD2 ▸ IFNA16 ▸ LTB ▸ CSF3 ▸ CCL3 ▸ IL1R1 ▸
CSK ▸ MMP19 ▸ TGFB3 ▸ MMP27 ▸ SPP1 ▸ MMP12 ▸ MMP25 ▸
TNFRSF1A ▸ MMP28 ▸ MSH3 ▸ MMP21 ▸ MMP17 ▸ MMP16 ▸ PLD1 ▸
MMP11 ▸ CXCL10 ▸ MMP10 ▸ EDN1 ▸ CAT ▸ NOD2 ▸ MMP20 ▸
EGR1 ▸ MMP15 ▸ MMP24 ▸ FGF1 ▸ ELANE ▸ HDAC1 ▸ SETD2 ▸
MMP26 ▸ CD4 ▸ QRICH1 ▸ NAALADL1 ▸ MSH2 ▸ TAB1 ▸ MSH6 ▸
CD8A ▸ FASLG ▸ SYT1 ▸ QRICH2 ▸ PLD4 ▸ TRAF6 ▸ FGF7 ▸
PLD3 ▸ MAP2K1 ▸ MSH5 ▸ PLD6 ▸ MSH4 ▸ ANGPT2 ▸ PLA2G1B ▸
AHR ▸ SST ▸ PLD5 ▸ CD38 ▸ HDAC6 ▸ FGF14 ▸ FGF18 ▸
CXCL1 ▸ LTF ▸ FGF19 ▸ FGF9 ▸ HSPD1 ▸ CD28 ▸ SELP ▸
SAA2 ▸ FGF3 ▸ TXN ▸ CSF1 ▸ CD46 ▸ FGF20 ▸ FGF13 ▸
HMOX1 ▸ FGF23 ▸ ADIPOQ ▸ FGF6 ▸ CSRP1 ▸ ITGB1 ▸ RAC1 ▸
STX2 ▸ NGF ▸ STAT1 ▸ FGF11 ▸ FGF8 ▸ FGF22 ▸ P2RY6 ▸
PDLIM7 ▸ C1QB ▸ FGF4 ▸ PPARG ▸ TNFSF12 ▸ SELL ▸ FGF10 ▸
SOCS3 ▸ FGF16 ▸ HDAC3 ▸ FGF21 ▸ HDAC5 ▸ C1QA ▸ ETS1 ▸
FGF5 ▸ FGF12 ▸ FGF17 ▸ NAP1L4 ▸ SETBP1 ▸ PDCD11 ▸ MUC21 ▸
PRTN3 ▸ CD79A ▸ HDAC10 ▸ NPS ▸ HSPB1 ▸ RHOA ▸ TNFSF13B ▸
MUC15 ▸ IL2RA ▸ MUC6 ▸ CXCR3 ▸ MUC22 ▸ MUC19 ▸ SAA4 ▸
CXCR4 ▸ RBBP4 ▸ PF4 ▸ HDAC4 ▸ MUC20 ▸ BCL3 ▸ MUC13 ▸
PLA2G4A ▸ ANGPT1 ▸ MUC8 ▸ PPARA ▸ MTOR ▸ HSPG2 ▸ RBBP7 ▸
PDGFB ▸ MUC17 ▸ ECM1 ▸ GPI ▸ APC ▸ ECM2 ▸ TRPV1 ▸
RHO ▸ CR1 ▸ ITIH4 ▸ MUC16 ▸ CD8B ▸ MUC4 ▸ HDAC9 ▸
HDAC8 ▸ TAT ▸ PLAU ▸ MUC12 ▸ PRKCD ▸ MUC7 ▸ HES1 ▸
STX1A ▸ HDAC7 ▸ ANG ▸ MTX1 ▸ ST8SIA2 ▸ CFTR ▸ HDAC11 ▸
STAT4 ▸ AGTR2 ▸ CISH ▸ TNMD ▸ MUC2 ▸ CPOX ▸ PRKAB2 ▸
IBD8 ▸ MT4 ▸ AZU1 ▸ ETS2 ▸ MT3 ▸ CXCL17 ▸ CHI3L1 ▸
EMD ▸ PRR24 ▸ PRKAB1 ▸ PRR15 ▸ CALM1 ▸ EPO ▸ UTP3 ▸
CTNNB1 ▸ PRR22 ▸ TGFA ▸ MUC5AC ▸ IBD5 ▸ FGG ▸ HES7 ▸
DUSP1 ▸ LPL ▸ OSM ▸ CALM2 ▸ MAP2K7 ▸ UTP23 ▸ TF ▸
FOXO3 ▸ ICAM5 ▸ MPL ▸ FCGR1A ▸ ADAM11 ▸ FGA ▸ PRKCA ▸
PRR5 ▸ PGD ▸ CCR5 ▸ PRKAA1 ▸ UTP20 ▸ IBD9 ▸ IBD7 ▸
PRKAG1 ▸ PRR19 ▸ IL17F ▸ CXCL11 ▸ CXCL6 ▸ PKD1 ▸ PRR4 ▸
NR4A2 ▸ MET ▸ CXCL9 ▸ RNASE3 ▸ IBD3 ▸ PRR16 ▸ SELPLG ▸
PRR21 ▸ IRAK3 ▸ CYP1A1 ▸ PRR18 ▸ PRR25 ▸ DEFA1 ▸ CCL20 ▸
IRAK1 ▸ HDC ▸ ROCK2 ▸ PRR13 ▸ PRKAA2 ▸ ICAM2 ▸ PRR12 ▸
JAK2 ▸ UTP18 ▸ ESR1 ▸ NUP43 ▸ UTP15 ▸ TFPI ▸ TAC1 ▸
SIGLEC7 ▸ HES4 ▸ IBD6 ▸ TAC4 ▸ NTS ▸ ELF4 ▸ PRL ▸
DDIT3 ▸ HES6 ▸ IFI44 ▸ TAC3 ▸ BRAF ▸ ADAM17 ▸ IBD2 ▸
NR0B1 ▸ ICOSLG ▸ ICAM3 ▸ PGF ▸ APEX1 ▸ ADCYAP1 ▸ GRP ▸
A2M ▸ PRR9 ▸ PRR3 ▸ BCL2 ▸ BCL10 ▸ ARG2 ▸ IBD4 ▸
PRDX2 ▸ TPO ▸ PRR7 ▸ ELF3 ▸ ARG1 ▸ SEA ▸ PTAFR ▸
SMAD3 ▸ ICAM4 ▸ RENBP ▸ HBEGF ▸ PRKAG2 ▸ PAEP ▸ MAP3K1 ▸
HES5 ▸ HES2 ▸ IL1R2 ▸ HES3 ▸ TP53 ▸ PRR11 ▸ UTP6 ▸
PRR14 ▸ PRR26 ▸ RELB ▸ CAPN10 ▸ SPP2 ▸ GHRH ▸ GAST ▸
GRB7 ▸ DNASE1 ▸ TSC22D3 ▸ CAPN15 ▸ CAPN11 ▸ HRH1 ▸ CXCR6 ▸
HLA-DRB1 ▸ FGB ▸ TBP ▸ ALOX5 ▸ F7 ▸ MYO19 ▸ IGF2 ▸
CPB1 ▸ RABEPK ▸ NFKBIZ ▸ CXCL3 ▸ RETN ▸ PAK1 ▸ DPM3 ▸
FCGR2B ▸ CYP1A2 ▸ NPY4R ▸ HMGB2 ▸ HCG27 ▸ KSR2 ▸ WNT3 ▸
POU2F1 ▸ SLPI ▸ CD1D ▸ HCG22 ▸ SCARB1 ▸ RAC2 ▸ HCG18 ▸
MAP2K6 ▸ PAK3 ▸ NLRP3 ▸ THBD ▸ ASIP ▸ MTA2 ▸ JAK1 ▸
PAK6 ▸ ADM ▸ PTGS1 ▸ FUT3 ▸ FUT4 ▸ TACR1 ▸ PTPN11 ▸
CAPN1 ▸ ALX3 ▸ CXCL13 ▸ TNPO1 ▸ CXCL2 ▸ IDO1 ▸ MAPKAPK2 ▸
CAPN3 ▸ HCG23 ▸ SMAD1 ▸ HMGB3 ▸ CAPN14 ▸ KRT10 ▸ PROK1 ▸
ELF2 ▸ HCG25 ▸ FOXO4 ▸ CNR1 ▸ CD83 ▸ CAPN13 ▸ MRXS5 ▸
CSH2 ▸ CTGF ▸ PTPN22 ▸ CAPN7 ▸ HCG21 ▸ KLK3 ▸ CP ▸
PAH ▸ ANPEP ▸ FCER2 ▸ CD44 ▸ TNFRSF1B ▸ F2RL2 ▸ MBP ▸
CDH5 ▸ CD163 ▸ ADAM10 ▸ KDR ▸ DPM2 ▸ PARK2 ▸ CAPN8 ▸
ADAM19 ▸ SYK ▸ HCG14 ▸ APOE ▸ CDC42 ▸ CX3CL1 ▸ SMAD6 ▸
GSTM1 ▸ NR4A1 ▸ WNT2 ▸ RAC3 ▸ CEBPB ▸ SPESP1 ▸ MAP2K3 ▸
JAK3 ▸ FUT7 ▸ FUT5 ▸ CXCL16 ▸ TNP2 ▸ VAV1 ▸ APOA1 ▸
ELAVL1 ▸ PGP ▸ SERPINB2 ▸ PINK1 ▸ VASP ▸ RNASE2 ▸ AR ▸
CA1 ▸ WNT16 ▸ MTA3 ▸ PAK4 ▸ ABL1 ▸ NPY ▸ FUT6 ▸
MEFV ▸ TNFSF11 ▸ HCG17 ▸ CXCL14 ▸ BPI ▸ TRNAI1 ▸ FUT10 ▸
FUT9 ▸ MTA1 ▸ HCG8 ▸ TPT1 ▸ GAL ▸ MYO10 ▸ MYO6 ▸
ALX1 ▸ TNFRSF9 ▸ F10 ▸ HCG26 ▸ TRAF2 ▸ HCG15 ▸ LBP ▸
HCG24 ▸ ALX4 ▸ CEBPA ▸ CSTA ▸ BCR ▸ VDR ▸ CSH1 ▸
WNT4 ▸ CAPN6 ▸ NPY6R ▸ REL ▸ S100A9 ▸ FOXO1 ▸ CCL5 ▸
C1orf228 ▸ FUT1 ▸ WNT1 ▸ CD69 ▸ IL23A ▸ SERPINE2 ▸ MAP2K2 ▸
ARSA ▸ DUOX1 ▸ FOXP3 ▸ BMP2 ▸ CAPN5 ▸ PDCD4 ▸ PITX1 ▸
HRAS ▸ ELF1 ▸ SFXN1 ▸ ACKR3 ▸ FUT2 ▸ FMR1 ▸ ITGA5 ▸
TMSB4X ▸ DNASE2 ▸ MEPE ▸ PDGFA ▸ CXCL5 ▸ MPG ▸ GRB14 ▸
HMGB4 ▸ WNT6 ▸ VCP ▸ CTSS ▸ FGFR2 ▸ MYO16 ▸ HIF1A ▸
ATP8A2 ▸ PARK7 ▸ ELF5 ▸ FOSL1 ▸ C3 ▸ BCL6 ▸ NAMPT ▸
SMAD5 ▸ MAP2K5 ▸ FOXO6 ▸ PAK2 ▸ SOAT1 ▸ WNT11 ▸ PTHLH ▸
IRS1 ▸ KLRB1 ▸ UCN2 ▸ CYP19A1 ▸ IFIH1 ▸ GH1 ▸ CPB2 ▸
MAP2K4 ▸ CAPN12 ▸ DPM1 ▸ FXYD1 ▸ FUT8 ▸ DDX58 ▸ GRPR ▸
HCG9 ▸ RAG1 ▸ SMAD7 ▸ SMAD4 ▸ CGN ▸ PAK7 ▸ SMAD9 ▸
BLM ▸ AREG ▸ SMAD2 ▸ FUT11 ▸ STAT5A ▸ HCG20 ▸ CAPN9 ▸
HCG16 ▸ CTSB ▸ CD2 ▸ GRB2 ▸ GRB10 ▸ CCL4 ▸ AGTR1 ▸
APOA2 ▸ CAPN2 ▸ MKNK1 ▸ CDH1 ▸ HCG11 ▸ CEACAM1 ▸ ROCK1 ▸
TEC ▸ GIP ▸ CEACAM6 ▸ CNR2 ▸ DEFA1B ▸ HBD ▸ HCG4 ▸
OXA1L ▸ TNP1 ▸ CD86 ▸ TAS2R41 ▸ TAS2R8 ▸ TAS2R5 ▸ TAS2R3 ▸
TAS2R9 ▸ TAS2R30 ▸ CHRM4 ▸ MTNR1A ▸ NPY2R ▸ S1PR4 ▸ HTR1A ▸
CCR4 ▸ OPRL1 ▸ PYY ▸ GRM8 ▸ P2RY4 ▸ CCL27 ▸ CCR7 ▸
S1PR2 ▸ TAS2R38 ▸ RXFP4 ▸ HTR1B ▸ PENK ▸ GPER1 ▸ TAS2R7 ▸
FPR3 ▸ GABBR1 ▸ RXFP3 ▸ OXGR1 ▸ HEBP1 ▸ NPY5R ▸ ADORA3 ▸
TAS2R16 ▸ ANXA1 ▸ SUCNR1 ▸ TAS2R46 ▸ CCR9 ▸ GRM2 ▸ S1PR5 ▸
GRM4 ▸ SSTR1 ▸ NPBWR1 ▸ GRM6 ▸ NPY1R ▸ TAS2R60 ▸ CCL19 ▸
GABBR2 ▸ MTNR1B ▸ MCHR2 ▸ U2AF1 ▸ CCL25 ▸ PTGDR2 ▸ APLNR ▸
DRD4 ▸ TAS2R14 ▸ PPBP ▸ ADRA2B ▸ GNB1 ▸ TAS2R19 ▸ NPBWR2 ▸
TAS2R40 ▸ GALR1 ▸ HRH3 ▸ PNOC ▸ KNG1 ▸ HCAR3 ▸ HCAR1 ▸
GRM3 ▸ TAS2R4 ▸ S1PR1 ▸ ADRA2C ▸ ADORA1 ▸ MCHR1 ▸ TAS2R50 ▸
TAS2R42 ▸ CX3CR1 ▸ GRM7 ▸ HRH4 ▸ TAS2R45 ▸ PPY ▸ CCR8 ▸
TAS2R31 ▸ TAS2R1 ▸ PDYN ▸ CCL16 ▸ CCR10 ▸ BDKRB1 ▸ S1PR3 ▸
XCR1 ▸ TAS2R10 ▸ OPRD1 ▸ SSTR2 ▸ MT-RNR2 ▸ P2RY12 ▸ CCR1 ▸
HTR5A ▸ DRD2 ▸ HTR1E ▸ NMUR2 ▸ CHRM2 ▸ GALR2 ▸ TAS2R20 ▸
GNAT3 ▸ CCL28 ▸ GNG2 ▸ PMCH ▸ NPB ▸ GNAI2 ▸ CCR2 ▸
DRD3 ▸ C3AR1 ▸ P2RY13 ▸ HCAR2 ▸ DARC ▸ SSTR3 ▸ SSTR4 ▸
TAS2R43 ▸ BDKRB2 ▸ ADRA2A ▸ GNAI3 ▸ HTR1D ▸ OXER1 ▸ TAS2R13 ▸
TAS2R39 ▸ OPRK1 ▸ CCR6 ▸ GNAI1 ▸ FPR1 ▸ INSL5 ▸ C5AR1 ▸
SSTR5 ▸ PTGER3 ▸ GALR3 ▸ HTR1F ▸ NMUR1 ▸ NMU ▸ LPAR5 ▸
Data information
Please see the Gene Interactions Track Manual.