Gene interactions and pathways from curated databases and text-mining
CASP3: top 25 interacting genes (chr4:185548849-185570601)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only CASP3-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with CASP3, not among the Top 25
Other genes interacting with CASP3. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

AKT3 ▸ XIAP ▸ IL1B ▸ FASLG ▸ MAPK3 ▸ BCL3 ▸ DIABLO ▸
BCL6 ▸ BCL9 ▸ IL1A ▸ BCL5 ▸ IRF6 ▸ EPHB2 ▸ MAPK1 ▸
MAPK4 ▸ MAPK8 ▸ MAPK9 ▸ MAPK13 ▸ MAPK10 ▸ MAPK12 ▸ MAPK15 ▸
MAPK6 ▸ MAPK7 ▸ MAPK11 ▸ MAPK14 ▸ IFNG ▸ CASP9 ▸ CASP8 ▸
APAF1 ▸ CASP12 ▸ CASP1 ▸ CASP2 ▸ CAPN1 ▸ CAPN10 ▸ DNTT ▸
CAPN13 ▸ CAPN12 ▸ CAPN15 ▸ CAPN14 ▸ CAPN7 ▸ CAPN2 ▸ CAPN9 ▸
CASP6 ▸ CAPN5 ▸ IL18 ▸ CAPN6 ▸ CAPN3 ▸ CAPN8 ▸ CAPN11 ▸
FADD ▸ CASP7 ▸ CASP16 ▸ CASP5 ▸ CASP4 ▸ CASP10 ▸ CASP14 ▸
ASIP ▸ STS ▸ MCL1 ▸ MMP2 ▸ MMP9 ▸ MMP11 ▸ MMP14 ▸
MMP12 ▸ MMP3 ▸ JUN ▸ NLRP3 ▸ MMP8 ▸ MMP15 ▸ MMP21 ▸
MMP26 ▸ MMP17 ▸ MMP13 ▸ MMP25 ▸ MMP7 ▸ CDKN1A ▸ MMP24 ▸
MMP27 ▸ MMP19 ▸ MMP1 ▸ MMP10 ▸ MMP28 ▸ MMP16 ▸ MMP20 ▸
PDCD5 ▸ PDCD11 ▸ PDCD10 ▸ PDCD7 ▸ PDCD2 ▸ RNF19A ▸ PDCD1 ▸
PDCD4 ▸ PDCD6 ▸ CFLAR ▸ CYCS ▸ NA ▸ IGF1 ▸ PCBD1 ▸
ANXA5 ▸ TGFB1 ▸ AHSA1 ▸ HLA-DRB1 ▸ MPZ ▸ INS ▸ PIK3CA ▸
PIK3R1 ▸ EPO ▸ NLRC4 ▸ PRKCD ▸ VEGFA ▸ PI3 ▸ MYLIP ▸
DDIT3 ▸ TAT ▸ PCNA ▸ IL6 ▸ DFFA ▸ NOS2 ▸ GRAP2 ▸
PRDX2 ▸ TNFRSF1A ▸ GSK3B ▸ CTSB ▸ NGF ▸ SOD1 ▸ EGF ▸
DISC1 ▸ BIRC2 ▸ PAK2 ▸ DISC2 ▸ CRK ▸ IL8 ▸ IL4 ▸
CTNNB1 ▸ PTGS2 ▸ CAST ▸ EIF2AK2 ▸ BID ▸ DFFB ▸ NOS1 ▸
LEP ▸ ROCK1 ▸ DNASE1 ▸ HGF ▸ ABL1 ▸ MYC ▸ SOD2 ▸
P2RX7 ▸ APP ▸ IRF1 ▸ DNASE2 ▸ ALPI ▸ FOS ▸ IFNB1 ▸
MAP3K1 ▸ CAT ▸ APEH ▸ CTSD ▸ CDK2 ▸ IL16 ▸ TCF4 ▸
HTRA2 ▸ BCR ▸ BDNF ▸ IFI27 ▸ BIRC7 ▸ CSF2 ▸ NOD2 ▸
NFKBIA ▸ TLR2 ▸ BMP4 ▸ TCF24 ▸ BMP1 ▸ TCF20 ▸ PRKDC ▸
NOX1 ▸ HDAC2 ▸ BIRC3 ▸ GZMB ▸ GAL ▸ UPK3B ▸ FGF2 ▸
SOD3 ▸ TCF15 ▸ TCF7 ▸ TCF19 ▸ TCF25 ▸ TCF12 ▸ RAC1 ▸
RIPK1 ▸ TCF21 ▸ NOS3 ▸ HSPA5 ▸ TCF23 ▸ APOB ▸ IL10 ▸
TCF3 ▸ PML ▸ MAGT1 ▸ LMNB1 ▸ AIM2 ▸ STAT1 ▸ NLRP1 ▸
BAD ▸ ARSK ▸ MAP2K1 ▸ ADCYAP1 ▸ CD8A ▸ POLDIP2 ▸ NOX4 ▸
IL2 ▸ TLR4 ▸ CSF3 ▸ HMGB1 ▸ HDAC1 ▸ PPARA ▸ CA2 ▸
CDC73 ▸ ATP5O ▸ ITIH4 ▸ TLR3 ▸ CDK5 ▸ ENDOG ▸ CD79A ▸
LEO1 ▸ PRNP ▸ BMP3 ▸ NOX5 ▸ CTR9 ▸ BMP5 ▸ TLR7 ▸
AGTR1 ▸ RIPK2 ▸ IL11 ▸ IL3 ▸ PAF1 ▸ HPR ▸ PPP2CA ▸
APC ▸ IL33 ▸ BMP15 ▸ PPP2R1A ▸ PPP2R2B ▸ SNAP25 ▸ RB1 ▸
HSPB1 ▸ PDLIM7 ▸ STAT3 ▸ BMP2 ▸ KRT18 ▸ MST1 ▸ CARD8 ▸
IL5 ▸ TLR5 ▸ NOX3 ▸ IL7 ▸ BMP10 ▸ SMPD2 ▸ BMP6 ▸
BMP7 ▸ NOD1 ▸ RAD51 ▸ WDR61 ▸ SMARCC2 ▸ SMARCA4 ▸ ABCC6 ▸
JAK2 ▸ IL15 ▸ TNFRSF1B ▸ BIRC6 ▸ EGFR ▸ CD4 ▸ ICAM1 ▸
TRAF6 ▸ RBBP7 ▸ HTT ▸ GP9 ▸ TXN ▸ CSE ▸ GP2 ▸
CREB5 ▸ PTX4 ▸ ANGPT2 ▸ IL24 ▸ FOXO3 ▸ IL21 ▸ IGF2 ▸
LMNB2 ▸ CREB1 ▸ CREB3 ▸ ARID1A ▸ IL20 ▸ CDH1 ▸ IL25 ▸
BOC ▸ ACTL6A ▸ TLR10 ▸ TLR1 ▸ ANXA1 ▸ PGP ▸ SMARCD2 ▸
PLCG1 ▸ NPS ▸ CDC6 ▸ RIPK3 ▸ SMARCE1 ▸ TLR8 ▸ CXCL9 ▸
SYK ▸ MET ▸ SMARCD1 ▸ WAS ▸ EIF2S1 ▸ MAP2K2 ▸ HIF1A ▸
GSN ▸ ANGPT1 ▸ PTX3 ▸ SMARCB1 ▸ SMARCC1 ▸ GP5 ▸ LPA ▸
RBBP4 ▸ SMARCA2 ▸ CCDC88A ▸ GP6 ▸ BECN1 ▸ IL19 ▸ MUC8 ▸
IL37 ▸ MUC16 ▸ MUC15 ▸ IL32 ▸ HSPD1 ▸ RAF1 ▸ TLR6 ▸
ROCK2 ▸ IL34 ▸ GATA1 ▸ IL13 ▸ IL26 ▸ UCN ▸ MUC17 ▸
MUC21 ▸ MUC7 ▸ SMPD1 ▸ MDM2 ▸ PPARG ▸ STX1A ▸ CDA ▸
TOP1 ▸ MUC22 ▸ SYT1 ▸ TRAF1 ▸ KDR ▸ MEFV ▸ CARD9 ▸
MUC1 ▸ PRKCA ▸ MUC2 ▸ IKBKB ▸ LYN ▸ MUC20 ▸ SP1 ▸
MUC19 ▸ HMOX1 ▸ BRCA1 ▸ MUC4 ▸ TLR9 ▸ MUC13 ▸ IL27 ▸
IRF3 ▸ MUC6 ▸ RRAS ▸ CCND1 ▸ CD79B ▸ ACHE ▸ MSC ▸
PLD1 ▸ IL9 ▸ CARD11 ▸ PTEN ▸ PAK1 ▸ RENBP ▸ CARD6 ▸
CDK8 ▸ IL22 ▸ MUC12 ▸ IL31 ▸ VCP ▸ SLCO6A1 ▸ CEP95 ▸
H2AFX ▸ PANX1 ▸ CEP63 ▸ HUNK ▸ PTK2 ▸ DES ▸ IRF4 ▸
EPX ▸ CEP76 ▸ MAP2K6 ▸ WNT1 ▸ PRKAR2B ▸ TIMP3 ▸ ELAVL1 ▸
CEP350 ▸ CEP135 ▸ FOXO1 ▸ SLC9A1 ▸ GUCY2D ▸ CEP70 ▸ CTSL ▸
ATF2 ▸ HIST2H2BE ▸ NTF3 ▸ CARD16 ▸ PRKAG2 ▸ CEP57 ▸ GDNF ▸
PIDD ▸ SETBP1 ▸ CEP112 ▸ GRB10 ▸ DERL1 ▸ CARD10 ▸ BACE1 ▸
ME2 ▸ GRB2 ▸ NPM1 ▸ MPST ▸ PRKAR1A ▸ PSMD10 ▸ CEP85 ▸
HIP1 ▸ ARSA ▸ IRF2 ▸ CEP152 ▸ PRKAA2 ▸ FUT1 ▸ PTHLH ▸
CEP164 ▸ CEP19 ▸ SUB1 ▸ SOAT1 ▸ E2F1 ▸ WNK1 ▸ CALM3 ▸
DST ▸ IGF1R ▸ SEC14L2 ▸ ATG5 ▸ TNFRSF10A ▸ SKP1 ▸ NPY6R ▸
VIMP ▸ TRAF3 ▸ ARC ▸ PRKAR2A ▸ ZGLP1 ▸ MAP2K4 ▸ CEP104 ▸
SETD2 ▸ PRKCG ▸ CEP44 ▸ GRB7 ▸ CEP68 ▸ PSEN1 ▸ PNPLA2 ▸
PLD2 ▸ IRF5 ▸ CCR7 ▸ CEP89 ▸ CEP78 ▸ CD47 ▸ EHMT1 ▸
PTBP1 ▸ CEP170 ▸ PLOD2 ▸ TARDBP ▸ MAP2K7 ▸ BCL2L12 ▸ LYPLA1 ▸
CEP120 ▸ PRKAB1 ▸ CARD14 ▸ CD40 ▸ CEP97 ▸ TCHP ▸ CCL2 ▸
ADIPOQ ▸ CCNH ▸ PEA15 ▸ MIF ▸ RAD17 ▸ BIRC8 ▸ ATF5 ▸
PRKAA1 ▸ GRB14 ▸ CEP55 ▸ CTNND1 ▸ MAP2K5 ▸ IKBKG ▸ BIRC5 ▸
CEP72 ▸ PRKACB ▸ CEP128 ▸ CEP41 ▸ RASA1 ▸ HSP90AA1 ▸ PRKAB2 ▸
LAT ▸ TRAF2 ▸ CDK4 ▸ PRKACG ▸ CARD17 ▸ HSF1 ▸ MAP2K3 ▸
SLC17A5 ▸ CEP192 ▸ ALB ▸ CUL1 ▸ PPP1R3A ▸ CARD18 ▸ PRKAG1 ▸
CEP290 ▸ PRKAR1B ▸ VDAC1 ▸ ALK ▸ CEP250 ▸ VIM ▸ CRYAB ▸
HDAC4 ▸ NAB1 ▸ HTRA1 ▸ GPX1 ▸ TRA ▸ MTA3 ▸ PAN3 ▸
CCL19 ▸ FAM168B ▸ EML2 ▸ ITCH ▸ PARG ▸ C22orf29 ▸ NUP62 ▸
CDK10 ▸ CDK14 ▸ GNA11 ▸ HTRA4 ▸ BNIP3 ▸ LGALS1 ▸ GPI ▸
RIPK4 ▸ MST1R ▸ ACAD8 ▸ MICE ▸ MED13 ▸ ETS1 ▸ PLD6 ▸
RHO ▸ MTX1 ▸ FKBP4 ▸ TET1 ▸ IFNA5 ▸ SDS ▸ PTPN11 ▸
NODAL ▸ NANOS2 ▸ CFL1 ▸ ATM ▸ TRAF4 ▸ COP ▸ DAP3 ▸
EIF4G3 ▸ RAD18 ▸ EIF4G2 ▸ E2F2 ▸ MED1 ▸ ANXA6 ▸ CCR2 ▸
GRP ▸ CCNC ▸ MTA1 ▸ CCR10 ▸ SERP2 ▸ TRAF5 ▸ CDC42 ▸
CD8B ▸ NAB2 ▸ LRRC59 ▸ MED7 ▸ SERPINA1 ▸ CALB1 ▸ SATB1 ▸
KLK3 ▸ TGFB3 ▸ SHH ▸ CDK7 ▸ THBS1 ▸ GPX3 ▸ CAPNS1 ▸
MED4 ▸ HCLS1 ▸ PLD5 ▸ JAK3 ▸ NUP214 ▸ NUP210 ▸ TNFSF12 ▸
CALR ▸ UCP2 ▸ NACA ▸ KLKB1 ▸ CDK15 ▸ ADH5 ▸ IRF9 ▸
DLG1 ▸ CISH ▸ SERPINF1 ▸ EDNRA ▸ CCR9 ▸ SPP1 ▸ S100A12 ▸
ERVK-6 ▸ STC1 ▸ PAN2 ▸ ABCD1 ▸ CCK ▸ MT4 ▸ GSTT1 ▸
IL1RN ▸ MED14 ▸ AIP ▸ DIDO1 ▸ EMP1 ▸ CDK17 ▸ DAPK2 ▸
PGF ▸ IRS1 ▸ CCR1 ▸ NPPA ▸ ING1 ▸ RAD50 ▸ RARA ▸
PXN ▸ MED21 ▸ VIP ▸ CDK18 ▸ PDGFB ▸ EMP2 ▸ TYR ▸
RAD21 ▸ DNAJC5 ▸ NANOG ▸ CHUK ▸ MED15 ▸ IRF7 ▸ CDK1 ▸
CA8 ▸ QRICH1 ▸ RAD1 ▸ FAF1 ▸ IFNA2 ▸ NAIP ▸ TGM2 ▸
HIPK2 ▸ HMGCR ▸ EMP3 ▸ MED25 ▸ PSMB9 ▸ SMAD7 ▸ CCR8 ▸
NTF4 ▸ SLPI ▸ ODC1 ▸ HTRA3 ▸ HRD ▸ CSF1 ▸ IRF8 ▸
CPOX ▸ CDK16 ▸ RAD52 ▸ ACR ▸ CYR61 ▸ MED24 ▸ PIN1 ▸
APEX1 ▸ DAXX ▸ SHC1 ▸ SEPT4 ▸ ATG3 ▸ CXCL13 ▸ NUP153 ▸
NOTCH1 ▸ CCR5 ▸ MT3 ▸ CCR3 ▸ CDK20 ▸ CDK13 ▸ CFTR ▸
CENPK ▸ STSP1 ▸ IDO1 ▸ APIP ▸ TET2 ▸ BLM ▸ MED26 ▸
RUNX3 ▸ HRK ▸ CCR4 ▸ NUP43 ▸ ANG ▸ BCAP31 ▸ CDK3 ▸
PLD4 ▸ CTNNBL1 ▸ ANGPT4 ▸ NLRC5 ▸ PRG3 ▸ PMEL ▸ CDK9 ▸
PPT1 ▸ PRG4 ▸ DHCR24 ▸ SAA1 ▸ GYS1 ▸ EEF1A2 ▸ PAWR ▸
WNT3A ▸ HDAC6 ▸ FHIT ▸ QRICH2 ▸ MED23 ▸ MAP2 ▸ CDK6 ▸
DYRK1A ▸ PC ▸ RAC2 ▸ TFAP2A ▸ NUAK1 ▸ GHSR ▸ TAC1 ▸
ACSM3 ▸ FLT3 ▸ CCR6 ▸ XRCC6 ▸ IAPP ▸ IFI44 ▸ SIVA1 ▸
XAF1 ▸ PSENEN ▸ TNFRSF8 ▸ SREBF2 ▸ MTOR ▸ RBL2 ▸ TRAF7 ▸
EIF4G1 ▸ ETS2 ▸ TET3 ▸ APOBEC3D ▸ GJA1 ▸ CPA1 ▸ VDAC2 ▸
SMAD4 ▸ TAC3 ▸ STX2 ▸ PLD3 ▸ SERPINB9 ▸ RAC3 ▸ AFP ▸
KMT2A ▸ BAG3 ▸ CD2 ▸ CIB1 ▸ PLK1 ▸ KLF4 ▸ JAK1 ▸
ACIN1 ▸ ADM ▸ MED6 ▸ E2F3 ▸ PRG2 ▸ PTH ▸ MED12 ▸
CALML3 ▸ CDK19 ▸ MAP3K7 ▸ TMED7 ▸ GLI1 ▸ MED8 ▸ MME ▸
MED17 ▸ ANP32A ▸ GNRH1 ▸ APOE ▸ TSC22D3 ▸ NR0B1 ▸ SMAD3 ▸
TNFRSF10B ▸ NTN1 ▸ CTRL ▸ IGFBP3 ▸ TAC4 ▸ VDAC3 ▸ IFIH1 ▸
LRP1 ▸ CDK12 ▸ CDCA5 ▸ SREBF1 ▸ PTCH1 ▸ MTA2 ▸ NLRP5 ▸
NLRP7 ▸ ID3 ▸ PAEP ▸ GYS2 ▸ WNK3 ▸ BMX ▸ GMNN ▸
IL1R2 ▸ PTMA ▸ NGFR ▸ PIP5K1A ▸ TP73 ▸ PPARGC1A ▸ PLA2G4B ▸
DSG2 ▸ NFE2L2 ▸ PLA2G4A ▸ IFT57 ▸ ACVR1C ▸ COPS6 ▸ HRAS ▸
PRF1 ▸ NMT2 ▸ PLEKHO1 ▸ BIRC4 ▸ PSIP1 ▸ ACTA1 ▸ NVL ▸
ATN1 ▸ HNRNPU ▸ EIF3S10 ▸ ELANE ▸ STK24 ▸ CDC2L1 ▸ SARS2 ▸
ZBTB16 ▸ LPAR1 ▸ NDUFS1 ▸ EIF3J ▸ ATG4D ▸ ARHGDIA ▸ MAP3K14 ▸
SAV1 ▸ PPP3CA ▸ SCAF11 ▸ FUS ▸ AIFM1 ▸ HNRNPD ▸ EIF4B ▸
MLH1 ▸ NR3C1 ▸ RNF2 ▸ NEO1 ▸ IQGAP1 ▸ FBXW11 ▸ DBNL ▸
UBC ▸ YWHAE ▸ YWHAG ▸ BCAR1 ▸ CDC2L2 ▸ PDE10A ▸ MDC1 ▸
CD247 ▸ MAPT ▸ MAP4K1 ▸ EIF4A1 ▸ KEAP1 ▸ RBX1 ▸ SOCS5 ▸
DSG1 ▸ PTGES3 ▸ LPAR3 ▸ NUCB2 ▸ TNFRSF25 ▸ NUMA1 ▸ CAD ▸
ARHGDIB ▸ NFATC2 ▸ RABEP1 ▸ DSG3 ▸ PICALM ▸ CTTN ▸ PDE5A ▸
UBE4B ▸ HEY2 ▸ SYF2 ▸ CDK11A ▸ SDC2 ▸ IL1R1 ▸ GRIPAP1 ▸
NGFRAP1 ▸ GAS2 ▸ MEF2A ▸ TNS4 ▸ DCTN1 ▸ GORASP1 ▸ CDK11B ▸
UNC5B ▸ THAP11 ▸ HNRNPA0 ▸ GZMM ▸ AR ▸ KARS ▸ TRIM28 ▸
MAPK8IP3 ▸ AKAP8 ▸ FUK ▸
Data information
Please see the Gene Interactions Track Manual.