Gene interactions and pathways from curated databases and text-mining
AKT1: top 25 interacting genes (chr14:105235685-105262085)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only AKT1-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
Gene:               Hide non-AKT1 interactions     Show top Genes on graph    

Less-frequently mentioned interactions with AKT1, not among the Top 25
Other genes interacting with AKT1. Mouse-over to show number of abstracts or databases. Sorted alphabetically (sort by article count).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

ABCA1 ABCB1 ABCG2 ABI1 ABL1 ACAP1 ACD
ACIN1 ACLY ACO1 ACTA1 ADA ADAM17 ADCY1
ADCY10 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7
ADCY8 ADCY9 ADCYAP1 ADIPOQ ADO ADRBK1 AGAP2
AGTR1 AGTR2 AHNAK AHSA1 AK1 AKT1S1 AKT2
AKT3 ALDOA ALK ALYREF AMPH ANG ANGPT1
ANGPT2 ANXA2 ANXA6 APC APLN APLP2 APOA1
APOB APOE APOH APP APPL1 AR AREG
ARFIP2 ARHGAP29 ARHGAP32 ARHGAP33 ARHGEF2 ARHGEF6 ARHGEF7
ARNT ARRB2 ARSK ASXL1 ATF1 ATF6B ATG5
ATM ATP1A1 ATP5O ATP6V0A2 ATR ATXN1 AURKA
AXIN2 AXL BAD BAG4 BAX BCL10 BCL2
BCL2L1 BCL2L11 BCL3 BCL5 BCL6 BCL9 BCR
BCRP1 BCRP2 BCRP3 BCRP4 BCRP5 BCRP6 BCRP7
BCRP8 BCRP9 BDNF BECN1 BIRC2 BIRC5 BMI1
BMP1 BMP10 BMP15 BMP2 BMP3 BMP4 BMP5
BMP6 BMP7 BMX BPGM BPI BPNT1 BRAF
BRCA1 BSG BTBD10 BTC BTK BTRC C5
CA2 CALM1 CALM2 CALM3 CAMK2A CAMK2B CAMKK1
CAMKK2 CAP1 CAPN1 CAPN10 CAPN11 CAPN12 CAPN13
CAPN14 CAPN15 CAPN2 CAPN3 CAPN5 CAPN6 CAPN7
CAPN8 CAPN9 CARD11 CASP2 CASP4 CASP5 CASP6
CASP7 CASP9 CAT CAV1 CAV2 CAV3 CBFA2T2
CBL CBLB CBLC CBY1 CCDC88A CCL11 CCL2
CCL20 CCL21 CCL24 CCL4 CCL5 CCL8 CCNB1
CCND1 CCND2 CCNG1 CCR2 CCR5 CCR7 CD19
CD28 CD2AP CD34 CD36 CD38 CD40 CD40LG
CD79A CD79B CD8A CDC25B CDC37 CDC42 CDC73
CDCA2 CDCA3 CDCA4 CDCA5 CDCA7 CDCA8 CDH1
CDH10 CDH11 CDH12 CDH13 CDH15 CDH16 CDH17
CDH18 CDH19 CDH2 CDH20 CDH22 CDH23 CDH24
CDH26 CDH3 CDH4 CDH5 CDH6 CDH7 CDH8
CDH9 CDK1 CDK2 CDK4 CDK5 CDKN1A CDKN1B
CDKN2A CDKN2B CEACAM5 CEACAM6 CEBPA CFLAR CHEK1
CHKA CHN2 CHUK CIB1 CKB CLDN1 CLK2
CLTC CLU CMC4 CNR1 CNR2 CNTF CNTN1
CNTN2 COMMD1 CORO2A CPA1 CPE CPOX CPT2
CREB1 CREB3 CREB3L1 CREB3L2 CREB3L3 CREB3L4 CREB5
CRH CRK CROT CRP CRTC2 CSDC2 CSE
CSF1 CSF1R CSF2 CSF2RB CSF3 CSK CSN2
CSN3 CSNK1A1 CSNK1E CSNK2A1 CSRP1 CTF1 CTGF
CTLA4 CTNNB1 CTNND2 CTR9 CUL1 CX3CL1 CXCL1
CXCL10 CXCL11 CXCL12 CXCL13 CXCL14 CXCL16 CXCL17
CXCL2 CXCL3 CXCL5 CXCL6 CXCL9 CXCR1 CXCR3
CXCR4 CYBA CYLD CYP19A1 CYTH3 DAB1 DAB2IP
DCN DDIT3 DDIT4 DDX5 DEPTOR DHCR24 DLC1
DNAJB9 DNM1 DNM2 DNM3 DNMT1 DOCK1 DRD2
DST DVL2 DYNC1H1 DYNLL1 E2F1 E2F2 E2F3
E2F4 E2F5 E2F6 E2F7 E2F8 ECM1 ECM2
EDC3 EDN1 EDN2 EDN3 EDNRA EEF1A2 EEF1G
EFNB1 EHD1 EHD2 EHMT1 EIF4A1 EIF4E EIF4EBP1
ELAVL1 ELMO1 ENG ENO1 EP300 EPHA2 EPHA3
EPO EPX ERBB2 ERBB3 ERBB4 ERF ESR1
ESR2 ETS1 ETS2 ETV6 EZH2 F2 F2R
F2RL1 F2RL3 FAM110C FAM129A FAS FASLG FASN
FBXO32 FCGR1A FCGR2B FGB FGF1 FGF10 FGF11
FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19
FGF2 FGF20 FGF21 FGF22 FGF23 FGF3 FGF4
FGF5 FGF6 FGF7 FGF8 FGF9 FGFR1 FGFR2
FGFR3 FGFR4 FKBP4 FKBP5 FLOT1 FLOT2 FLT3
FLT4 FOS FOSL1 FOXO1 FOXO3 FOXO4 FOXO6
FOXP3 FRS2 FSCN1 FST FSTL1 FUT1 FUT4
FUT7 FYN G6PC GAB1 GAB2 GADD45A GALT
GAPDH GAS1 GAS6 GAST GATA1 GCG GCK
GCLC GDA GDF15 GDNF GGA1 GGA2 GGA3
GH1 GHSR GIP GJA1 GLI1 GLI2 GNA11
GNA12 GNA13 GNA14 GNA15 GNB1 GNRH1 GNRH2
GP1BA GP1BB GP2 GP5 GP6 GP9 GPER1
GPI GPR1 GPR101 GPR107 GPR108 GPR110 GPR111
GPR112 GPR113 GPR114 GPR115 GPR116 GPR119 GPR12
GPR123 GPR124 GPR125 GPR126 GPR128 GPR132 GPR133
GPR135 GPR137 GPR139 GPR141 GPR142 GPR143 GPR144
GPR146 GPR148 GPR149 GPR15 GPR150 GPR151 GPR152
GPR153 GPR155 GPR156 GPR157 GPR158 GPR160 GPR161
GPR162 GPR17 GPR171 GPR173 GPR174 GPR176 GPR179
GPR18 GPR180 GPR182 GPR183 GPR19 GPR20 GPR21
GPR22 GPR25 GPR26 GPR27 GPR3 GPR31 GPR32
GPR33 GPR34 GPR35 GPR36 GPR37 GPR39 GPR4
GPR42 GPR45 GPR50 GPR52 GPR55 GPR56 GPR6
GPR61 GPR62 GPR63 GPR64 GPR65 GPR68 GPR75
GPR78 GPR79 GPR82 GPR83 GPR84 GPR85 GPR87
GPR88 GPR97 GPR98 GPS2 GRAP2 GRB10 GRB14
GRB2 GRIP1 GRK1 GRK4 GRK5 GRK6 GRK7
GRM1 GRP GSK3A GSK3B GTPBP1 GTPBP10 GTPBP2
GTPBP3 GTPBP4 GTPBP6 GTPBP8 GYS1 GYS2 HBB
HBEGF HDAC1 HDAC10 HDAC11 HDAC2 HDAC3 HDAC4
HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HGF HIF1A
HIST2H2BE HK1 HK2 HK3 HLA-DRA HMGB1 HMOX1
HOXD13 HPSE HRAS HRG HRH3 HSP90AA1 HSPA4
HSPA5 HSPB1 HSPCA HSPD1 HSPG2 HTR1B HTT
IARS IBTK ICAM1 ICAM2 ICAM3 ID1 IFI27
IFI44 IFNB1 IFNG IFNGR2 IGF1R IGF2 IGFBP1
IGFBP2 IGFBP3 IGFBP4 IGFBP5 IGFBP6 IGFBP7 IGSF8
IKBKB IKBKE IKBKG IL10 IL11 IL13 IL17A
IL18 IL1A IL1B IL2 IL21 IL22 IL24
IL3 IL31 IL32 IL33 IL34 IL4 IL5
IL6 IL7 IL8 ILK IMPDH2 INPP5D INPPL1
INSR IQGAP1 IQGAP2 IRAK2 IRF3 IRF6 IRS1
IRS2 IRS4 ITGA2B ITGA5 ITGA6 ITGAM ITGB1
ITGB3 ITLN1 ITPR1 JAK1 JAK2 JAK3 JUN
KAT2B KDR KHSRP KIF3A KIT KITLG KL
KLF4 KLF5 KLK1 KLK3 KRAS KRT10 KTN1
LAT LBH LDHA LEF1 LEO1 LEP LEPR
LGI3 LIF LILRB1 LIMS1 LOX LPA LPAR2
LRP1 LRP5 LRRK2 LTB LTB4R2 LTF LYN
LYPLA1 MALT1 MAP2K1 MAP2K4 MAP3K1 MAP3K11 MAP3K14
MAP3K5 MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK15
MAPK4 MAPK6 MAPK7 MAPK8 MAPK8IP1 MAPK9 MAPKAP1
MAPKAPK2 MAPT MARK2 MATK MBP MCAM MCL1
MDH1 MDM2 MECP2 MEFV MET METTL1 MICE
MIF MIP MKL1 MLST8 MLYCD MME MMP1
MMP10 MMP11 MMP12 MMP13 MMP14 MMP15 MMP16
MMP17 MMP19 MMP2 MMP20 MMP21 MMP24 MMP25
MMP26 MMP27 MMP28 MMP3 MMP7 MMP8 MMP9
MPO MPZ MRE11A MS4A2 MST1 MSTN MT2A
MT3 MTA1 MTCP1 MTDH MUC1 MUC2 MUC4
MUC8 MUL1 MYC MYCN MYD88 MYH11 MYLIP
MYO1C MYOG NA NAMPT NANOG NCAM1 NCAM2
NCF1 NCOA1 NCOA3 NCOA4 NCOR1 NDRG2 NEDD4
NET1 NEUROD1 NEUROD2 NEUROD4 NEUROD6 NFATC1 NFKB2
NFKBIA NFKBIB NFKBIE NGB NGF NKX3-1 NOD1
NODAL NOS1 NOS2 NOTCH1 NOTCH2 NOTCH3 NOTCH4
NOX1 NOX3 NOX4 NOX5 NPPA NPPB NPS
NPY NPY4R NPY6R NR3C1 NR4A1 NRF1 NRG1
NRG2 NRG3 NRG4 NRIP1 NRP1 NSF NTF3
NTF4 NTN1 NTN4 NTRK1 NTRK2 NTRK3 NTS
NUP43 OGG1 OLR1 OPN1LW OPN1MW OSM P2RY12
P2RY2 PA2G4 PAEP PAF1 PAK1 PAK2 PAK3
PAK4 PAK6 PAK7 PARP1 PARP10 PARP11 PARP12
PARP14 PARP15 PARP16 PARP2 PARP3 PARP4 PARP6
PARP8 PARP9 PAWR PAX2 PAX3 PCK1 PCK2
PCNA PDCD1 PDCD10 PDCD11 PDCD2 PDCD4 PDCD5
PDCD6 PDCD7 PDE3B PDGFA PDGFB PDGFRA PDGFRB
PDK1 PDK2 PDK3 PDK4 PDLIM7 PDPK1 PEA15
PEBP1 PEBP4 PECAM1 PFKFB1 PFN1 PGC PGF
PHB2 PHKA2 PHLPP1 PI4K2B PIAS1 PIAS2 PIAS3
PIAS4 PIK3C2B PIK3C3 PIK3CB PIK3CG PIK3R2 PIK3R3
PIK3R4 PIK3R5 PIKFYVE PIM1 PIP PKN1 PKN2
PLA2G1B PLA2G4A PLAT PLAU PLCG1 PLCG2 PLD1
PLD2 PLD3 PLD4 PLD5 PLD6 PLEK PLK1
PLXNA1 PLXNB1 PML POLDIP2 POT1 POU5F1 PPA1
PPARA PPARG PPARGC1A PPARGC1B PPIA PPP1CB PPP1CC
PPP1R12A PPP1R1B PPP1R3A PPP1R3B PPP1R3C PPP1R3D PPP2CA
PPP2R1A PPP2R1B PPP2R2B PPP2R2C PPP2R2D PPP2R3A PPP2R3C
PPP2R4 PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PPP3CA
PPT1 PRDX2 PRG2 PRG3 PRG4 PRKAA1 PRKAA2
PRKAB1 PRKAB2 PRKACB PRKACG PRKAG1 PRKAG2 PRKAG3
PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCB PRKCQ
PRKCZ PRKDC PRL PRNP PROK1 PRPH2 PRR5
PSEN1 PSEN2 PSMB9 PSMD10 PTGER2 PTGER4 PTGES
PTGS2 PTH PTHLH PTK2 PTK6 PTK7 PTP4A3
PTPN1 PTPN11 PTPN2 PTX3 PTX4 PXN RAB5A
RAC1 RAC2 RAC3 RAD1 RAD17 RAD18 RAD21
RAD50 RAD51 RAD52 RAF1 RALGDS RAP1B RAPGEF1
RAPGEF3 RARA RARB RASA1 RB1 RBBP4 RBBP7
RBL2 RBP1 RBP4 RELN REN RET RETN
RGCC RGS2 RGS4 RHEB RHEBL1 RHO RHOA
RHOB RHOJ RHOQ RICTOR RIPK1 RIPK2 RLN1
RLN2 RLN3 RNF19A RNF5 RPL17 RPS6 RPS6KB1
RPTOR RRAS RUNX2 RXRB RXRG S100B S1PR1
S1PR2 S1PR3 SCARB1 SDC4 SDCBP SDF2 SDF4
SERPINA12 SERPINA4 SERPINB5 SERPINE1 SERTAD4 SETD2 SETDB1
SFI1 SFN SFTPC SGK1 SH2B1 SH2B2 SH2B3
SHC1 SHH SIGMAR1 SIM2 SIRT1 SIRT6 SKI
SKP1 SKP2 SLAMF1 SLC22A3 SLC25A16 SLC25A22 SLC2A1
SLC2A3 SLC2A4 SLC2A4RG SLC2A5 SLC6A3 SLC8A1 SLC9A1
SLC9A3 SLC9A3R1 SLC9A3R2 SMAD1 SMAD2 SMAD3 SMAD4
SMAD5 SMAD6 SMAD7 SMAD9 SMO SNAI2 SNAP23
SNAP25 SNCA SNX1 SOAT1 SOCS1 SOCS3 SOCS6
SOD1 SOD2 SOD3 SORBS1 SORT1 SOX9 SP1
SPARC SPHK1 SPHK2 SPP1 SPRY2 SRC SREBF1
SST STAT1 STAT3 STAT5A STK10 STK11 STK16
STK19 STK24 STK25 STK3 STK31 STK33 STK35
STK36 STK38 STK39 STK4 STK40 STRN STS
STUB1 STX4 STXBP1 STXBP2 STXBP3 STXBP4 STYK1
SYK SYT1 TAC1 TAC3 TAC4 TACR1 TAS2R13
TAT TBC1D1 TBC1D4 TBK1 TBL1X TBL1XR1 TCF12
TCF15 TCF19 TCF20 TCF21 TCF23 TCF24 TCF25
TCF3 TCF4 TCF7 TCHP TCL1A TEP1 TERF1
TERF2 TERF2IP TERT TFAM TGFA TGFB1 TGFB2
TGFB3 TGFBI TGM2 TGM5 TGM7 THEM4 THPO
THRA TIE1 TIMP1 TIMP2 TINF2 TLR1 TLR10
TLR2 TLR3 TLR4 TLR5 TLR6 TLR7 TLR8
TLR9 TMED7 TNFRSF11B TNFRSF1A TNFRSF1B TNFSF10 TNFSF11
TNFSF13B TNK2 TNS2 TP53 TP73 TPM2 TPM4
TPO TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6
TRAF7 TRB TRHDE TRIB3 TRIM72 TRIP6 TSC1
TSC2 TSC22D3 TSN TTC3 TUBB4B TWIST1 TXN
TXNDC9 TXNIP TYR TYRP1 UBA52 UBC UBE2D1
UCHL1 UCN UTP15 UTP18 UTP20 UTP23 UTP3
UTP6 UTRN UVRAG UXS1 VAMP2 VAV1 VCAM1
VCP VDR VEGFC VIM VLDLR VWF WAS
WDR61 WNK1 WNT1 WNT11 WNT16 WNT2 WNT3
WNT3A WNT4 WNT6 XBP1 XIAP XRCC5 XRCC6
YAP1 YBX1 YWHAB YWHAQ ZEB2 ZGLP1 ZHX1
ZYX
Data information
Please see the Gene Interactions Track Manual.