Human Gene PLCXD1 (ENST00000381657.8_7) from GENCODE V45lift37
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Sequence and Links to Tools and Databases
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Comments and Description Text from UniProtKB
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ID: PLCX1_HUMAN
DESCRIPTION: RecName: Full=PI-PLC X domain-containing protein 1;
SUBCELLULAR LOCATION: Cytoplasm TISSUE SPECIFICITY: Widely expressed. MISCELLANEOUS: The gene coding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.
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Primer design for this transcript
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Comparative Toxicogenomics Database (CTD)
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Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
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Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
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The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
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Protein Domain and Structure Information
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InterPro Domains: Graphical view of domain structure IPR017946 - PLC-like_Pdiesterase_TIM-brl
IPR042158 - PLCXD1/2/3
IPR000909 - PLipase_C_PInositol-sp_X_dom
Pfam Domains: PF00388 - Phosphatidylinositol-specific phospholipase C, X domain
ModBase Predicted Comparative 3D Structure on Q9NUJ7
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
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Gene Ontology (GO) Annotations with Structured Vocabulary
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Molecular Function: GO:0008081 phosphoric diester hydrolase activity
Biological Process: GO:0006629 lipid metabolic process
Cellular Component: GO:0005737 cytoplasm
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Descriptions from all associated GenBank mRNAs
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AK002185 - Homo sapiens cDNA FLJ11323 fis, clone PLACE1010362, weakly similar to 1-PHOSPHATIDYLINOSITOL PHOSPHODIESTERASE PRECURSOR (EC 3.1.4.10). BC064136 - Homo sapiens phosphatidylinositol-specific phospholipase C, X domain containing 1, mRNA (cDNA clone IMAGE:6526328). BC005028 - Homo sapiens phosphatidylinositol-specific phospholipase C, X domain containing 1, mRNA (cDNA clone MGC:12582 IMAGE:3953383), complete cds. BC000888 - Homo sapiens phosphatidylinositol-specific phospholipase C, X domain containing 1, mRNA (cDNA clone IMAGE:3462893). BC032072 - Homo sapiens phosphatidylinositol-specific phospholipase C, X domain containing 1, mRNA (cDNA clone IMAGE:3462894). JD476599 - Sequence 457623 from Patent EP1572962. JD439212 - Sequence 420236 from Patent EP1572962. JD399984 - Sequence 381008 from Patent EP1572962. CU678870 - Synthetic construct Homo sapiens gateway clone IMAGE:100018918 5' read PLCXD1 mRNA. KJ899133 - Synthetic construct Homo sapiens clone ccsbBroadEn_08527 PLCXD1 gene, encodes complete protein. HQ447796 - Synthetic construct Homo sapiens clone IMAGE:100071139; CCSB005097_01 phosphatidylinositol-specific phospholipase C, X domain containing 1 (PLCXD1) gene, encodes complete protein. JD532536 - Sequence 513560 from Patent EP1572962. JD158399 - Sequence 139423 from Patent EP1572962. JD152709 - Sequence 133733 from Patent EP1572962. JD282104 - Sequence 263128 from Patent EP1572962. JD224742 - Sequence 205766 from Patent EP1572962. JD407851 - Sequence 388875 from Patent EP1572962. JD181976 - Sequence 163000 from Patent EP1572962. JD441506 - Sequence 422530 from Patent EP1572962. DL492017 - Novel nucleic acids. DL490569 - Novel nucleic acids. JD258190 - Sequence 239214 from Patent EP1572962. JD536553 - Sequence 517577 from Patent EP1572962. JD459836 - Sequence 440860 from Patent EP1572962. JD131536 - Sequence 112560 from Patent EP1572962. JD413476 - Sequence 394500 from Patent EP1572962. JD247065 - Sequence 228089 from Patent EP1572962. JD247066 - Sequence 228090 from Patent EP1572962. JD194942 - Sequence 175966 from Patent EP1572962. JD136322 - Sequence 117346 from Patent EP1572962. JD280822 - Sequence 261846 from Patent EP1572962. AK091006 - Homo sapiens cDNA FLJ33687 fis, clone BRAWH2002725. AX746727 - Sequence 252 from Patent EP1308459. JD397055 - Sequence 378079 from Patent EP1572962. JD414836 - Sequence 395860 from Patent EP1572962. JD415715 - Sequence 396739 from Patent EP1572962. JD252881 - Sequence 233905 from Patent EP1572962. JD094127 - Sequence 75151 from Patent EP1572962. JD429094 - Sequence 410118 from Patent EP1572962. JD311817 - Sequence 292841 from Patent EP1572962. JD311818 - Sequence 292842 from Patent EP1572962. DQ586065 - Homo sapiens piRNA piR-53177, complete sequence. AK097346 - Homo sapiens cDNA FLJ40027 fis, clone STOMA2008614. BC033659 - Homo sapiens phosphatidylinositol-specific phospholipase C, X domain containing 1, mRNA (cDNA clone IMAGE:4394596), containing frame-shift errors. JD476733 - Sequence 457757 from Patent EP1572962. JD414834 - Sequence 395858 from Patent EP1572962. JD311809 - Sequence 292833 from Patent EP1572962. JD311810 - Sequence 292834 from Patent EP1572962. JD081610 - Sequence 62634 from Patent EP1572962. JD181043 - Sequence 162067 from Patent EP1572962. JD081611 - Sequence 62635 from Patent EP1572962. JD465278 - Sequence 446302 from Patent EP1572962. JD418709 - Sequence 399733 from Patent EP1572962. JD258978 - Sequence 240002 from Patent EP1572962. JD257895 - Sequence 238919 from Patent EP1572962. JD293690 - Sequence 274714 from Patent EP1572962. JD465943 - Sequence 446967 from Patent EP1572962. JD409332 - Sequence 390356 from Patent EP1572962. JD256549 - Sequence 237573 from Patent EP1572962. JD476735 - Sequence 457759 from Patent EP1572962. JD520380 - Sequence 501404 from Patent EP1572962. JD406295 - Sequence 387319 from Patent EP1572962. JD557993 - Sequence 539017 from Patent EP1572962. JD172891 - Sequence 153915 from Patent EP1572962. JD376640 - Sequence 357664 from Patent EP1572962. JD414838 - Sequence 395862 from Patent EP1572962. JD414837 - Sequence 395861 from Patent EP1572962. JD379689 - Sequence 360713 from Patent EP1572962. JD311819 - Sequence 292843 from Patent EP1572962. JD311820 - Sequence 292844 from Patent EP1572962. JD081616 - Sequence 62640 from Patent EP1572962. JD512120 - Sequence 493144 from Patent EP1572962. JD348208 - Sequence 329232 from Patent EP1572962. JD129567 - Sequence 110591 from Patent EP1572962.
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Other Names for This Gene
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Alternate Gene Symbols: A2BH51, A2BH52, ENST00000381657.1, ENST00000381657.2, ENST00000381657.3, ENST00000381657.4, ENST00000381657.5, ENST00000381657.6, ENST00000381657.7, NR_163416, PLCX1_HUMAN, Q9NUJ7, uc318qka.1 UCSC ID: ENST00000381657.8_7 RefSeq Accession: NM_018390
Protein: Q9NUJ7
(aka PLCX1_HUMAN)
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Methods, Credits, and Use Restrictions
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Click here
for details on how this gene model was made and data restrictions if any.
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