Human Gene NHLRC3 (ENST00000379599.6_2) from GENCODE V45lift37
Description: Homo sapiens NHL repeat containing 3 (NHLRC3), transcript variant 2, mRNA. (from RefSeq NM_001017370) RefSeq Summary (NM_001017370): This gene encodes a protein containing NCL-1, HT2A and Lin-41 (NHL) family repeats. Mammalian NHL-repeat containing proteins may be involved in a variety of enzymatic processes, including protein modification through ubiquitination. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Aug 2012]. Gencode Transcript: ENST00000379599.6_2 Gencode Gene: ENSG00000188811.14_7 Transcript (Including UTRs) Position: hg19 chr13:39,612,528-39,624,246 Size: 11,719 Total Exon Count: 6 Strand: + Coding Region Position: hg19 chr13:39,612,777-39,622,063 Size: 9,287 Coding Exon Count: 6
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q5JS37
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0061630 ubiquitin protein ligase activity
Biological Process: GO:0000209 protein polyubiquitination GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043312 neutrophil degranulation
Cellular Component: GO:0005576 extracellular region GO:0035578 azurophil granule lumen