Human Gene ACIN1 (ENST00000605057.6_8) from GENCODE V45lift37
Description: apoptotic chromatin condensation inducer 1 (from HGNC ACIN1) RefSeq Summary (NM_014977): Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]. Gencode Transcript: ENST00000605057.6_8 Gencode Gene: ENSG00000100813.15_15 Transcript (Including UTRs) Position: hg19 chr14:23,527,773-23,564,345 Size: 36,573 Total Exon Count: 19 Strand: - Coding Region Position: hg19 chr14:23,528,357-23,564,321 Size: 35,965 Coding Exon Count: 19
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on S4R3H4
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Gene Ontology (GO) Annotations with Structured Vocabulary
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
